rs6442433

Homo sapiens
C>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0207 (6199/29948,GnomAD)
G=0189 (5520/29118,TOPMED)
G=0144 (721/5008,1000G)
G=0217 (835/3854,ALSPAC)
G=0217 (804/3708,TWINSUK)
chr3:14234259 (GRCh38.p7) (3p25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
72 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.14234259C>G
GRCh37.p13 chr 3NC_000003.11:g.14275759C>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.849G=0.151
1000GenomesAmericanSub694C=0.860G=0.140
1000GenomesEast AsianSub1008C=0.895G=0.105
1000GenomesEuropeSub1006C=0.759G=0.241
1000GenomesGlobalStudy-wide5008C=0.856G=0.144
1000GenomesSouth AsianSub978C=0.920G=0.080
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.783G=0.217
The Genome Aggregation DatabaseAfricanSub8718C=0.833G=0.167
The Genome Aggregation DatabaseAmericanSub838C=0.860G=0.140
The Genome Aggregation DatabaseEast AsianSub1622C=0.920G=0.080
The Genome Aggregation DatabaseEuropeSub18468C=0.758G=0.241
The Genome Aggregation DatabaseGlobalStudy-wide29948C=0.793G=0.207
The Genome Aggregation DatabaseOtherSub302C=0.860G=0.140
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.810G=0.189
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.783G=0.217
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs64424330.000722alcohol dependence21314694

eQTL of rs6442433 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6442433 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr31424460314245616E067-30143
chr31425225214253096E067-22663
chr31429033614290976E06714577
chr31429118614291468E06715427
chr31429755514297678E06721796
chr31429773114297802E06721972
chr31429792914298109E06722170
chr31429812614298373E06722367
chr31424460314245616E068-30143
chr31425327014253360E068-22399
chr31429033614290976E06814577
chr31429118614291468E06815427
chr31429755514297678E06821796
chr31429773114297802E06821972
chr31429792914298109E06822170
chr31429812614298373E06822367
chr31430261814303140E06826859
chr31424460314245616E069-30143
chr31425327014253360E069-22399
chr31425342414253509E069-22250
chr31429033614290976E06914577
chr31429118614291468E06915427
chr31429755514297678E06921796
chr31429773114297802E06921972
chr31429792914298109E06922170
chr31429812614298373E06922367
chr31430261814303140E06926859
chr31429755514297678E07021796
chr31429773114297802E07021972
chr31429792914298109E07022170
chr31429812614298373E07022367
chr31425225214253096E071-22663
chr31425327014253360E071-22399
chr31425342414253509E071-22250
chr31429033614290976E07114577
chr31429118614291468E07115427
chr31429755514297678E07121796
chr31429773114297802E07121972
chr31429792914298109E07122170
chr31429812614298373E07122367
chr31430261814303140E07126859
chr31424460314245616E072-30143
chr31425327014253360E072-22399
chr31425342414253509E072-22250
chr31429033614290976E07214577
chr31429118614291468E07215427
chr31429755514297678E07221796
chr31429773114297802E07221972
chr31429792914298109E07222170
chr31429812614298373E07222367
chr31430261814303140E07226859
chr31429033614290976E07314577
chr31429118614291468E07315427
chr31429755514297678E07321796
chr31429773114297802E07321972
chr31429792914298109E07322170
chr31429812614298373E07322367
chr31430261814303140E07326859
chr31424460314245616E074-30143
chr31425225214253096E074-22663
chr31425327014253360E074-22399
chr31425342414253509E074-22250
chr31428908214289161E07413323
chr31429033614290976E07414577
chr31429118614291468E07415427
chr31429755514297678E07421796
chr31429773114297802E07421972
chr31429792914298109E07422170
chr31429812614298373E07422367
chr31430261814303140E07426859
chr31432072614320880E08144967
chr31432105714321299E08145298









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr31425768814258608E067-17151
chr31425768814258608E068-17151
chr31425768814258608E069-17151
chr31425768814258608E070-17151
chr31425768814258608E071-17151
chr31425768814258608E072-17151
chr31425768814258608E073-17151
chr31425768814258608E074-17151
chr31425768814258608E081-17151
chr31425768814258608E082-17151