SNP Detail Info-rs6443523

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0358 (10701/29858,GnomAD)
A=0421 (12258/29118,TOPMED)
A=0496 (2485/5008,1000G)
A=0186 (716/3854,ALSPAC)
A=0191 (709/3708,TWINSUK)

Position: chr3:177987280 (GRCh38.p7) (3q26.32)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.177987280G>A
GRCh37.p13 chr 3	NC_000003.11:g.177705068G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.280	A=0.720
1000Genomes	American	Sub	694	G=0.650	A=0.350
1000Genomes	East Asian	Sub	1008	G=0.417	A=0.583
1000Genomes	Europe	Sub	1006	G=0.797	A=0.203
1000Genomes	Global	Study-wide	5008	G=0.504	A=0.496
1000Genomes	South Asian	Sub	978	G=0.490	A=0.510
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.814	A=0.186
The Genome Aggregation Database	African	Sub	8684	G=0.350	A=0.650
The Genome Aggregation Database	American	Sub	830	G=0.650	A=0.350
The Genome Aggregation Database	East Asian	Sub	1608	G=0.431	A=0.569
The Genome Aggregation Database	Europe	Sub	18434	G=0.795	A=0.204
The Genome Aggregation Database	Global	Study-wide	29858	G=0.641	A=0.358
The Genome Aggregation Database	Other	Sub	302	G=0.750	A=0.250
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.579	A=0.421
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.809	A=0.191

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs6443523	3.66E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs6443523