SNP Detail Info-rs6445588

Molecule type	Change	Amino acid[Codon]	SO Term
CACNA1D transcript variant 1	NM_000720.3:c.	N/A	Intron Variant
CACNA1D transcript variant 3	NM_001128839.2:c.	N/A	Intron Variant
CACNA1D transcript variant 2	NM_001128840.2:c.	N/A	Intron Variant
CACNA1D transcript variant X12	XM_005265448.3:c.	N/A	Intron Variant
CACNA1D transcript variant X2	XM_011534094.2:c.	N/A	Intron Variant
CACNA1D transcript variant X11	XM_011534096.2:c.	N/A	Intron Variant
CACNA1D transcript variant X13	XM_011534097.2:c.	N/A	Intron Variant
CACNA1D transcript variant X15	XM_011534100.2:c.	N/A	Intron Variant
CACNA1D transcript variant X1	XM_017007137.1:c.	N/A	Intron Variant
CACNA1D transcript variant X3	XM_017007138.1:c.	N/A	Intron Variant
CACNA1D transcript variant X4	XM_017007139.1:c.	N/A	Intron Variant
CACNA1D transcript variant X5	XM_017007140.1:c.	N/A	Intron Variant
CACNA1D transcript variant X6	XM_017007141.1:c.	N/A	Intron Variant
CACNA1D transcript variant X7	XM_017007142.1:c.	N/A	Intron Variant
CACNA1D transcript variant X8	XM_017007143.1:c.	N/A	Intron Variant
CACNA1D transcript variant X9	XM_017007144.1:c.	N/A	Intron Variant
CACNA1D transcript variant X10	XM_017007145.1:c.	N/A	Intron Variant
CACNA1D transcript variant X14	XM_011534099.2:c.	N/A	Genic Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.613	T=0.387
1000Genomes	American	Sub	694	C=0.800	T=0.200
1000Genomes	East Asian	Sub	1008	C=0.723	T=0.277
1000Genomes	Europe	Sub	1006	C=0.864	T=0.136
1000Genomes	Global	Study-wide	5008	C=0.736	T=0.264
1000Genomes	South Asian	Sub	978	C=0.740	T=0.260
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.862	T=0.138
The Genome Aggregation Database	African	Sub	8692	C=0.635	T=0.365
The Genome Aggregation Database	American	Sub	834	C=0.740	T=0.260
The Genome Aggregation Database	East Asian	Sub	1614	C=0.741	T=0.259
The Genome Aggregation Database	Europe	Sub	18482	C=0.868	T=0.131
The Genome Aggregation Database	Global	Study-wide	29924	C=0.790	T=0.209
The Genome Aggregation Database	Other	Sub	302	C=0.900	T=0.100
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.762	T=0.238
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.871	T=0.129

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs6445588	0.000326	Nicotine dependence (smoking)	19268276
rs6445588	0.000881	Nicotine initiation (smoking)	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr3	53651715	53651802	E067	21036
chr3	53584179	53584278	E068	-46401
chr3	53584389	53584632	E068	-46047
chr3	53583394	53583509	E070	-47170
chr3	53650328	53650855	E070	19649
chr3	53658032	53658095	E070	27353
chr3	53659978	53660120	E070	29299
chr3	53662673	53662830	E070	31994
chr3	53663060	53663145	E070	32381
chr3	53663300	53663433	E070	32621
chr3	53663467	53663552	E070	32788
chr3	53619213	53619373	E071	-11306
chr3	53619566	53619790	E071	-10889
chr3	53649693	53649933	E071	19014
chr3	53651715	53651802	E071	21036
chr3	53652286	53652368	E071	21607
chr3	53584179	53584278	E072	-46401
chr3	53650328	53650855	E072	19649
chr3	53652286	53652368	E072	21607
chr3	53584179	53584278	E073	-46401
chr3	53584389	53584632	E073	-46047
chr3	53584179	53584278	E074	-46401
chr3	53584389	53584632	E074	-46047
chr3	53619213	53619373	E074	-11306
chr3	53587207	53587339	E081	-43340
chr3	53587367	53587445	E081	-43234
chr3	53650137	53650187	E081	19458
chr3	53650328	53650855	E081	19649
chr3	53662673	53662830	E081	31994
chr3	53663060	53663145	E081	32381
chr3	53663300	53663433	E081	32621
chr3	53663467	53663552	E081	32788
chr3	53587207	53587339	E082	-43340
chr3	53587367	53587445	E082	-43234
chr3	53587634	53587752	E082	-42927

rs6445588