rs6454050

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0166 (4990/29966,GnomAD)
C=0204 (5950/29118,TOPMED)
C=0194 (974/5008,1000G)
C=0117 (449/3854,ALSPAC)
C=0108 (402/3708,TWINSUK)
chr6:63155077 (GRCh38.p7) (6q12)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.63155077T>C
GRCh37.p13 chr 6NC_000006.11:g.63864982T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.626C=0.374
1000GenomesAmericanSub694T=0.840C=0.160
1000GenomesEast AsianSub1008T=0.805C=0.195
1000GenomesEuropeSub1006T=0.886C=0.114
1000GenomesGlobalStudy-wide5008T=0.806C=0.194
1000GenomesSouth AsianSub978T=0.940C=0.060
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.883C=0.117
The Genome Aggregation DatabaseAfricanSub8704T=0.698C=0.302
The Genome Aggregation DatabaseAmericanSub838T=0.830C=0.170
The Genome Aggregation DatabaseEast AsianSub1622T=0.810C=0.190
The Genome Aggregation DatabaseEuropeSub18500T=0.898C=0.101
The Genome Aggregation DatabaseGlobalStudy-wide29966T=0.833C=0.166
The Genome Aggregation DatabaseOtherSub302T=0.880C=0.120
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.795C=0.204
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.892C=0.108
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs64540502.57E-05alcohol and nictotine co-dependence20158304

eQTL of rs6454050 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6454050 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.