rs6463401

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0328 (9790/29802,GnomAD)
A=0331 (9657/29118,TOPMED)
A=0321 (1609/5008,1000G)
A=0310 (1196/3854,ALSPAC)
A=0303 (1122/3708,TWINSUK)
chr7:47243291 (GRCh38.p7) (7p12.3)
ND
GWASdb2
1   publication(s)
See rs on genome
32 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.47243291G>A
GRCh37.p13 chr 7NC_000007.13:g.47282889G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.626A=0.374
1000GenomesAmericanSub694G=0.640A=0.360
1000GenomesEast AsianSub1008G=0.816A=0.184
1000GenomesEuropeSub1006G=0.659A=0.341
1000GenomesGlobalStudy-wide5008G=0.679A=0.321
1000GenomesSouth AsianSub978G=0.660A=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.690A=0.310
The Genome Aggregation DatabaseAfricanSub8628G=0.640A=0.360
The Genome Aggregation DatabaseAmericanSub836G=0.650A=0.350
The Genome Aggregation DatabaseEast AsianSub1616G=0.848A=0.152
The Genome Aggregation DatabaseEuropeSub18420G=0.671A=0.328
The Genome Aggregation DatabaseGlobalStudy-wide29802G=0.671A=0.328
The Genome Aggregation DatabaseOtherSub302G=0.660A=0.340
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.668A=0.331
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.697A=0.303
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs64634013.67E-05alcohol and nictotine co-dependence20158304

eQTL of rs6463401 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6463401 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr74732608947326156E06743200
chr74732616747326217E06743278
chr74727869947278755E068-4134
chr74728033947280577E068-2312
chr74729474047294897E06811851
chr74730559647307293E06822707
chr74729474047294897E06911851
chr74729474047294897E07111851
chr74729474047294897E07211851
chr74729474047294897E07311851
chr74723531547235562E081-47327
chr74723587547236294E081-46595
chr74723637347236490E081-46399
chr74723680247236870E081-46019
chr74723716547237515E081-45374
chr74723758047237722E081-45167
chr74723785347237987E081-44902
chr74725095847251029E081-31860
chr74725105447251640E081-31249
chr74725183347251883E081-31006
chr74725190447251954E081-30935
chr74725219047252254E081-30635
chr74725233847252392E081-30497
chr74725475747254874E081-28015
chr74729474047294897E08111851
chr74729495947295061E08112070
chr74730559647307293E08122707
chr74723587547236294E082-46595
chr74723758047237722E082-45167
chr74723785347237987E082-44902
chr74723809247238186E082-44703
chr74729474047294897E08211851