rs6466686

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0419 (12496/29802,GnomAD)
C==0471 (13716/29118,TOPMED)
C==0385 (1930/5008,1000G)
C==0372 (1434/3854,ALSPAC)
C==0359 (1330/3708,TWINSUK)
chr7:118996763 (GRCh38.p7) (7q31.31)
AD
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.118996763C>T
GRCh37.p13 chr 7NC_000007.13:g.118636817C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.657T=0.343
1000GenomesAmericanSub694C=0.300T=0.700
1000GenomesEast AsianSub1008C=0.329T=0.671
1000GenomesEuropeSub1006C=0.349T=0.651
1000GenomesGlobalStudy-wide5008C=0.385T=0.615
1000GenomesSouth AsianSub978C=0.170T=0.830
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.372T=0.628
The Genome Aggregation DatabaseAfricanSub8652C=0.602T=0.398
The Genome Aggregation DatabaseAmericanSub828C=0.280T=0.720
The Genome Aggregation DatabaseEast AsianSub1598C=0.314T=0.686
The Genome Aggregation DatabaseEuropeSub18422C=0.349T=0.650
The Genome Aggregation DatabaseGlobalStudy-wide29802C=0.419T=0.580
The Genome Aggregation DatabaseOtherSub302C=0.350T=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.471T=0.529
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.359T=0.641
PMID Title Author Journal
22613542ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior.Chen XDChin Med J (Engl)

P-Value

SNP ID p-value Traits Study
rs64666865.86E-08alcohol consumption22613542

eQTL of rs6466686 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6466686 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7118614632118614702E081-22115
chr7118614812118615340E081-21477
chr7118639808118640007E0812991
chr7118640023118640111E0813206
chr7118646613118646739E0819796
chr7118647292118647578E08110475