rs647852

Homo sapiens
A>G / A>T
None
Check p-value
SNV (Single Nucleotide Variation)
A==0180 (5406/29962,GnomAD)
A==0169 (4931/29118,TOPMED)
A==0123 (617/5008,1000G)
A==0212 (816/3854,ALSPAC)
A==0223 (827/3708,TWINSUK)
chr18:26734543 (GRCh38.p7) (18q11.2)
AD
GWASdb2
1   publication(s)
See rs on genome
11 Enhancers around
5 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.26734543A>G
GRCh38.p7 chr 18NC_000018.10:g.26734543A>T
GRCh37.p13 chr 18NC_000018.9:g.24314507A>G
GRCh37.p13 chr 18NC_000018.9:g.24314507A>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.113G=0.887
1000GenomesAmericanSub694A=0.100G=0.900
1000GenomesEast AsianSub1008A=0.008G=0.992
1000GenomesEuropeSub1006A=0.227G=0.773
1000GenomesGlobalStudy-wide5008A=0.123G=0.877
1000GenomesSouth AsianSub978A=0.160G=0.840
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.212G=0.788
The Genome Aggregation DatabaseAfricanSub8718A=0.134G=0.866
The Genome Aggregation DatabaseAmericanSub838A=0.130G=0.870
The Genome Aggregation DatabaseEast AsianSub1622A=0.004G=0.996
The Genome Aggregation DatabaseEuropeSub18482A=0.221G=0.778
The Genome Aggregation DatabaseGlobalStudy-wide29962A=0.180G=0.819
The Genome Aggregation DatabaseOtherSub302A=0.130G=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.169G=0.830
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.223G=0.777
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs6478527.98E-05alcohol consumption23953852

eQTL of rs647852 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs647852 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr185768750457687746E06723130
chr185768778857688281E06723414
chr185768778857688281E06823414
chr185768750457687746E06923130
chr185768778857688281E06923414
chr185768778857688281E07123414
chr185768750457687746E07423130
chr185768778857688281E07423414
chr185763644957636647E081-27727
chr185764734857647645E082-16729
chr185764769757647860E082-16514







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr185763681257636920E069-27454
chr185763681257636920E070-27454
chr185763707157637111E070-27263
chr185763681257636920E082-27454
chr185763707157637111E082-27263