SNP Detail Info-rs6481955

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

MALRD1 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0209 (6263/29932,GnomAD)
G=0285 (8314/29118,TOPMED)
G=0234 (1174/5008,1000G)
G=0109 (420/3854,ALSPAC)
G=0112 (415/3708,TWINSUK)

Position: chr10:19506116 (GRCh38.p7) (10p12.31)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 15 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 10	NC_000010.11:g.19506116A>G
GRCh37.p13 chr 10	NC_000010.10:g.19795045A>G

Molecule type	Change	Amino acid[Codon]	SO Term
MALRD1 transcript	NM_001142308.2:c.	N/A	Intron Variant
MALRD1 transcript variant X1	XM_011519453.2:c.	N/A	Intron Variant
MALRD1 transcript variant X2	XM_011519454.1:c.	N/A	Intron Variant
MALRD1 transcript variant X3	XM_011519455.2:c.	N/A	Intron Variant
MALRD1 transcript variant X4	XM_017016182.1:c.	N/A	Intron Variant
MALRD1 transcript variant X5	XM_017016183.1:c.	N/A	Intron Variant
MALRD1 transcript variant X7	XM_017016184.1:c.	N/A	Intron Variant
MALRD1 transcript variant X8	XM_017016185.1:c.	N/A	Intron Variant
MALRD1 transcript variant X9	XM_017016186.1:c.	N/A	Intron Variant
MALRD1 transcript variant X6	XR_001747102.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.490	G=0.510
1000Genomes	American	Sub	694	A=0.820	G=0.180
1000Genomes	East Asian	Sub	1008	A=0.865	G=0.135
1000Genomes	Europe	Sub	1006	A=0.904	G=0.096
1000Genomes	Global	Study-wide	5008	A=0.766	G=0.234
1000Genomes	South Asian	Sub	978	A=0.850	G=0.150
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.891	G=0.109
The Genome Aggregation Database	African	Sub	8694	A=0.546	G=0.454
The Genome Aggregation Database	American	Sub	836	A=0.830	G=0.170
The Genome Aggregation Database	East Asian	Sub	1608	A=0.858	G=0.142
The Genome Aggregation Database	Europe	Sub	18492	A=0.896	G=0.103
The Genome Aggregation Database	Global	Study-wide	29932	A=0.790	G=0.209
The Genome Aggregation Database	Other	Sub	302	A=0.890	G=0.110
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.714	G=0.285
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.888	G=0.112

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6481955	0.00074	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr10	19777603	19777755	E068	-17290
chr10	19777774	19778305	E068	-16740
chr10	19777603	19777755	E071	-17290
chr10	19777774	19778305	E071	-16740
chr10	19778309	19778435	E071	-16610
chr10	19777774	19778305	E072	-16740
chr10	19778309	19778435	E072	-16610
chr10	19777774	19778305	E073	-16740
chr10	19778309	19778435	E073	-16610
chr10	19777774	19778305	E074	-16740
chr10	19778309	19778435	E074	-16610
chr10	19777774	19778305	E081	-16740
chr10	19778309	19778435	E081	-16610
chr10	19777603	19777755	E082	-17290
chr10	19777774	19778305	E082	-16740

rs6481955