rs6484176

Homo sapiens
T>C
LOC105376596 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0300 (8983/29864,GnomAD)
C=0343 (10008/29118,TOPMED)
C=0272 (1361/5008,1000G)
C=0228 (878/3854,ALSPAC)
C=0235 (872/3708,TWINSUK)
chr11:25766084 (GRCh38.p7) (11p14.3)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.25766084T>C
GRCh37.p13 chr 11NC_000011.9:g.25787631T>C

Gene: LOC105376596, uncharacterized LOC105376596(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105376596 transcript variant X1XR_931132.2:n.N/AIntron Variant
LOC105376596 transcript variant X3XR_931134.1:n.N/AIntron Variant
LOC105376596 transcript variant X5XR_931135.2:n.N/AIntron Variant
LOC105376596 transcript variant X4XR_931136.2:n.N/AIntron Variant
LOC105376596 transcript variant X2XR_931133.2:n.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.477C=0.523
1000GenomesAmericanSub694T=0.780C=0.220
1000GenomesEast AsianSub1008T=0.920C=0.080
1000GenomesEuropeSub1006T=0.737C=0.263
1000GenomesGlobalStudy-wide5008T=0.728C=0.272
1000GenomesSouth AsianSub978T=0.830C=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.772C=0.228
The Genome Aggregation DatabaseAfricanSub8702T=0.534C=0.466
The Genome Aggregation DatabaseAmericanSub836T=0.810C=0.190
The Genome Aggregation DatabaseEast AsianSub1602T=0.917C=0.083
The Genome Aggregation DatabaseEuropeSub18422T=0.753C=0.246
The Genome Aggregation DatabaseGlobalStudy-wide29864T=0.699C=0.300
The Genome Aggregation DatabaseOtherSub302T=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.656C=0.343
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.765C=0.235
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs64841768.84E-07nicotine smoking19268276

eQTL of rs6484176 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6484176 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.