rs6492218

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0329 (9864/29920,GnomAD)
C==0386 (11257/29118,TOPMED)
C==0413 (2066/5008,1000G)
C==0196 (756/3854,ALSPAC)
C==0200 (742/3708,TWINSUK)
chr13:109673402 (GRCh38.p7) (13q34)
AD
GWASdb2
1   publication(s)
See rs on genome
88 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.109673402C>T
GRCh37.p13 chr 13NC_000013.10:g.110325749C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.637T=0.363
1000GenomesAmericanSub694C=0.280T=0.720
1000GenomesEast AsianSub1008C=0.446T=0.554
1000GenomesEuropeSub1006C=0.217T=0.783
1000GenomesGlobalStudy-wide5008C=0.413T=0.587
1000GenomesSouth AsianSub978C=0.370T=0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.196T=0.804
The Genome Aggregation DatabaseAfricanSub8708C=0.567T=0.433
The Genome Aggregation DatabaseAmericanSub838C=0.240T=0.760
The Genome Aggregation DatabaseEast AsianSub1606C=0.410T=0.590
The Genome Aggregation DatabaseEuropeSub18468C=0.214T=0.785
The Genome Aggregation DatabaseGlobalStudy-wide29920C=0.329T=0.670
The Genome Aggregation DatabaseOtherSub300C=0.360T=0.640
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.386T=0.613
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.200T=0.800
PMID Title Author Journal
21956439Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q.Zuo LNeuropsychopharmacology

P-Value

SNP ID p-value Traits Study
rs64922183E-06alcohol dependence21956439

eQTL of rs6492218 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6492218 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr13110372162110372274E06746413
chr13110373018110373145E06747269
chr13110373208110373418E06747459
chr13110373422110373516E06747673
chr13110320135110320702E068-5047
chr13110321048110321191E068-4558
chr13110321218110321764E068-3985
chr13110321780110321862E068-3887
chr13110321930110321994E068-3755
chr13110322008110322079E068-3670
chr13110322173110322265E068-3484
chr13110322282110322441E068-3308
chr13110322482110322538E068-3211
chr13110336829110337827E06811080
chr13110337880110337930E06812131
chr13110337953110338060E06812204
chr13110372162110372274E06846413
chr13110372307110372351E06846558
chr13110372436110372523E06846687
chr13110372559110372947E06846810
chr13110373018110373145E06847269
chr13110373208110373418E06847459
chr13110373422110373516E06847673
chr13110321218110321764E069-3985
chr13110321780110321862E069-3887
chr13110344294110344405E06918545
chr13110344425110344505E06918676
chr13110372559110372947E06946810
chr13110373018110373145E06947269
chr13110282187110282433E070-43316
chr13110320135110320702E070-5047
chr13110359403110359689E07033654
chr13110359759110360052E07034010
chr13110360325110360720E07034576
chr13110372162110372274E07046413
chr13110372307110372351E07046558
chr13110372436110372523E07046687
chr13110372559110372947E07046810
chr13110373018110373145E07047269
chr13110373208110373418E07047459
chr13110373422110373516E07047673
chr13110373902110373993E07048153
chr13110307438110307984E071-17765
chr13110308009110308194E071-17555
chr13110321048110321191E071-4558
chr13110336829110337827E07111080
chr13110344294110344405E07118545
chr13110372436110372523E07146687
chr13110372559110372947E07146810
chr13110373018110373145E07147269
chr13110373208110373418E07147459
chr13110372162110372274E07246413
chr13110372307110372351E07246558
chr13110372436110372523E07246687
chr13110372559110372947E07246810
chr13110373018110373145E07247269
chr13110373208110373418E07247459
chr13110373422110373516E07247673
chr13110322482110322538E073-3211
chr13110336829110337827E07311080
chr13110372162110372274E07346413
chr13110372307110372351E07346558
chr13110372436110372523E07346687
chr13110372559110372947E07346810
chr13110321218110321764E074-3985
chr13110321780110321862E074-3887
chr13110321930110321994E074-3755
chr13110322008110322079E074-3670
chr13110322173110322265E074-3484
chr13110322282110322441E074-3308
chr13110322482110322538E074-3211
chr13110336829110337827E07411080
chr13110338135110338190E07412386
chr13110372162110372274E07446413
chr13110372307110372351E07446558
chr13110372436110372523E07446687
chr13110372559110372947E07446810
chr13110373018110373145E07447269
chr13110373208110373418E07447459
chr13110373422110373516E07447673
chr13110282187110282433E081-43316
chr13110282187110282433E082-43316
chr13110289882110290019E082-35730
chr13110290095110290394E082-35355
chr13110317654110318458E082-7291
chr13110319484110319705E082-6044
chr13110319909110319963E082-5786
chr13110320135110320702E082-5047