SNP Detail Info-rs6493511

Molecule type	Change	Amino acid[Codon]	SO Term
DMXL2 transcript variant 1	NM_001174116.1:c.	N/A	Intron Variant
DMXL2 transcript variant 3	NM_001174117.1:c.	N/A	Intron Variant
DMXL2 transcript variant 2	NM_015263.3:c.	N/A	Intron Variant
DMXL2 transcript variant X1	XM_005254255.1:c.	N/A	Intron Variant
DMXL2 transcript variant X2	XM_005254256.1:c.	N/A	Intron Variant
DMXL2 transcript variant X12	XM_011521402.2:c.	N/A	Intron Variant
DMXL2 transcript variant X3	XM_017022034.1:c.	N/A	Genic Upstream Transcript Variant
DMXL2 transcript variant X6	XR_001751173.1:n.	N/A	Intron Variant
DMXL2 transcript variant X8	XR_001751174.1:n.	N/A	Intron Variant
DMXL2 transcript variant X9	XR_001751175.1:n.	N/A	Intron Variant
DMXL2 transcript variant X10	XR_001751176.1:n.	N/A	Intron Variant
DMXL2 transcript variant X11	XR_001751177.1:n.	N/A	Intron Variant
DMXL2 transcript variant X4	XR_931779.2:n.	N/A	Intron Variant
DMXL2 transcript variant X5	XR_931780.2:n.	N/A	Intron Variant
DMXL2 transcript variant X7	XR_931781.2:n.	N/A	Intron Variant
DMXL2 transcript variant X13	XR_931782.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.125	G=0.875
1000Genomes	American	Sub	694	A=0.180	G=0.820
1000Genomes	East Asian	Sub	1008	A=0.011	G=0.989
1000Genomes	Europe	Sub	1006	A=0.219	G=0.781
1000Genomes	Global	Study-wide	5008	A=0.130	G=0.870
1000Genomes	South Asian	Sub	978	A=0.130	G=0.870
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.230	G=0.770
The Genome Aggregation Database	African	Sub	8722	A=0.129	G=0.871
The Genome Aggregation Database	American	Sub	836	A=0.130	G=0.870
The Genome Aggregation Database	East Asian	Sub	1622	A=0.010	G=0.990
The Genome Aggregation Database	Europe	Sub	18476	A=0.207	G=0.792
The Genome Aggregation Database	Global	Study-wide	29958	A=0.172	G=0.827
The Genome Aggregation Database	Other	Sub	302	A=0.280	G=0.720
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.179	G=0.820
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.244	G=0.756

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6493511	0.000986	alcohol dependence	21314694

eQTL of rs6493511 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	1.7429e-13	-71945	Cerebellum
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	9.0703e-3	-71945	Cortex
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	3.9969e-16	-71945	Cerebellar_Hemisphere
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	5.7051e-6	-71945	Caudate_basal_ganglia
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	3.4280e-4	-71945	Brain_Spinal_cord_cervical
Chr15:51901605	SCG3	ENSG00000104112.4	A>G	4.9093e-4	-71945	Putamen_basal_ganglia

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr15	51909564	51909614	E067	7959
chr15	51910058	51910112	E067	8453
chr15	51910219	51910388	E067	8614
chr15	51912322	51912421	E067	10717
chr15	51912482	51912597	E067	10877
chr15	51912693	51912800	E067	11088
chr15	51916162	51916265	E067	14557
chr15	51910219	51910388	E068	8614
chr15	51921645	51921895	E071	20040
chr15	51922336	51922553	E071	20731
chr15	51910219	51910388	E074	8614
chr15	51912322	51912421	E081	10717
chr15	51912482	51912597	E081	10877
chr15	51912693	51912800	E081	11088

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr15	51913469	51913621	E067	11864
chr15	51913625	51916161	E067	12020
chr15	51913469	51913621	E068	11864
chr15	51913625	51916161	E068	12020
chr15	51913469	51913621	E069	11864
chr15	51913625	51916161	E069	12020
chr15	51913469	51913621	E070	11864
chr15	51913625	51916161	E070	12020
chr15	51913469	51913621	E071	11864
chr15	51913625	51916161	E071	12020
chr15	51913469	51913621	E072	11864
chr15	51913625	51916161	E072	12020
chr15	51913469	51913621	E073	11864
chr15	51913625	51916161	E073	12020
chr15	51913469	51913621	E074	11864
chr15	51913625	51916161	E074	12020
chr15	51913469	51913621	E081	11864
chr15	51913625	51916161	E081	12020
chr15	51913469	51913621	E082	11864
chr15	51913625	51916161	E082	12020

rs6493511