rs6504626

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0142 (4262/29916,GnomAD)
C=0135 (3933/29118,TOPMED)
C=0199 (995/5008,1000G)
C=0127 (488/3854,ALSPAC)
C=0144 (534/3708,TWINSUK)
chr17:49942527 (GRCh38.p7) (17q21.33)
AD
GWASdb2
1   publication(s)
See rs on genome
17 Enhancers around
2 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.49942527T>C
GRCh37.p13 chr 17NC_000017.10:g.48019891T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.849C=0.151
1000GenomesAmericanSub694T=0.790C=0.210
1000GenomesEast AsianSub1008T=0.729C=0.271
1000GenomesEuropeSub1006T=0.888C=0.112
1000GenomesGlobalStudy-wide5008T=0.801C=0.199
1000GenomesSouth AsianSub978T=0.730C=0.270
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.873C=0.127
The Genome Aggregation DatabaseAfricanSub8702T=0.855C=0.145
The Genome Aggregation DatabaseAmericanSub836T=0.780C=0.220
The Genome Aggregation DatabaseEast AsianSub1616T=0.774C=0.226
The Genome Aggregation DatabaseEuropeSub18460T=0.868C=0.131
The Genome Aggregation DatabaseGlobalStudy-wide29916T=0.857C=0.142
The Genome Aggregation DatabaseOtherSub302T=0.920C=0.080
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.864C=0.135
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.856C=0.144
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs65046260.000346alcohol dependence20201924

eQTL of rs6504626 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6504626 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr174806514548065223E06845254
chr174806707048067247E06847179
chr174806514548065223E06945254
chr174801288748012937E070-6954
chr174805463848054786E07034747
chr174806514548065223E07045254
chr174806514548065223E07145254
chr174802382248024015E0733931
chr174806487848064940E07344987
chr174806500248065054E07345111
chr174806514548065223E07345254
chr174798166547981715E081-38176
chr174806487848064940E08144987
chr174806500248065054E08145111
chr174806514548065223E08145254
chr174798225447982356E082-37535
chr174806514548065223E08245254







Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr174804540048046751E07425509
chr174804540048046751E08225509