rs6531366

Homo sapiens
A>C / A>G
None
Check p-value
SNV (Single Nucleotide Variation)
C=0485 (14509/29882,GnomAD)
A==0494 (14391/29118,TOPMED)
C=0479 (2397/5008,1000G)
chr4:35513892 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35513892A>C
GRCh38.p7 chr 4NC_000004.12:g.35513892A>G
GRCh37.p13 chr 4NC_000004.11:g.35515514A>C
GRCh37.p13 chr 4NC_000004.11:g.35515514A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.489C=0.511
1000GenomesAmericanSub694A=0.460C=0.540
1000GenomesEast AsianSub1008A=0.707C=0.293
1000GenomesEuropeSub1006A=0.535C=0.465
1000GenomesGlobalStudy-wide5008A=0.521C=0.479
1000GenomesSouth AsianSub978A=0.400C=0.600
The Genome Aggregation DatabaseAfricanSub8706A=0.492C=0.508
The Genome Aggregation DatabaseAmericanSub832A=0.430C=0.570
The Genome Aggregation DatabaseEast AsianSub1606A=0.740C=0.260
The Genome Aggregation DatabaseEuropeSub18436A=0.508C=0.491
The Genome Aggregation DatabaseGlobalStudy-wide29882A=0.514C=0.485
The Genome Aggregation DatabaseOtherSub302A=0.580C=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.494C=0.505
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs65313660.000378nicotine dependence17158188

eQTL of rs6531366 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6531366 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr44179893441799089E06933005
chr44179893441799089E07433005
chr44179923641799401E07433307
chr44173361741733973E081-31956
chr44174483141744899E081-21030
chr44174483141744899E082-21030