rs6532800

Homo sapiens
T>C / T>G
ADH4 : Intron Variant
LOC100507053 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0041 (1255/29986,GnomAD)
T==0036 (180/5008,1000G)
chr4:99137733 (GRCh38.p7) (4q23)
AD
GWASCatalog
1   publication(s)
See rs on genome
14 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.99137733T>C
GRCh38.p7 chr 4NC_000004.12:g.99137733T>G
GRCh37.p13 chr 4NC_000004.11:g.100058884T>C
GRCh37.p13 chr 4NC_000004.11:g.100058884T>G

Gene: ADH4, alcohol dehydrogenase 4 (class II), pi polypeptide(minus strand)

Molecule type Change Amino acid[Codon] SO Term
ADH4 transcript variant 3NM_000670.4:c.N/AIntron Variant
ADH4 transcript variant 1NM_001306171.1:c.N/AIntron Variant
ADH4 transcript variant 2NM_001306172.1:c.N/AIntron Variant
ADH4 transcript variant X1XM_017007713.1:c.N/AIntron Variant
ADH4 transcript variant X2XM_017007714.1:c.N/AIntron Variant
ADH4 transcript variant X3XM_017007715.1:c.N/AIntron Variant

Gene: LOC100507053, uncharacterized LOC100507053(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC100507053 transcriptNR_037884.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.070C=0.930
1000GenomesAmericanSub694T=0.060C=0.94,
1000GenomesEast AsianSub1008T=0.001C=0.999
1000GenomesEuropeSub1006T=0.026C=0.966
1000GenomesGlobalStudy-wide5008T=0.036C=0.962
1000GenomesSouth AsianSub978T=0.020C=0.98,
The Genome Aggregation DatabaseAfricanSub8730T=0.062G=0.002
The Genome Aggregation DatabaseAmericanSub836T=0.060G=0.01,
The Genome Aggregation DatabaseEast AsianSub1622T=0.001G=0.000
The Genome Aggregation DatabaseEuropeSub18496T=0.035G=0.005
The Genome Aggregation DatabaseGlobalStudy-wide29986T=0.041G=0.004
The Genome Aggregation DatabaseOtherSub302T=0.020G=0.00,
PMID Title Author Journal
24166409Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs65328001E-06alcohol dependence24166409

eQTL of rs6532800 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6532800 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr42678902626790245E06832057
chr42680490126805488E06847932
chr42678902626790245E07132057
chr42680490126805488E07247932
chr42678121326781721E08124244
chr42678188926782589E08124920
chr42679770726797802E08140738
chr42679784126798013E08140872
chr42679814926798203E08141180
chr42680471226804884E08147743
chr42680490126805488E08147932
chr42680611426806164E08149145
chr42680628626806443E08149317
chr42678121326781721E08224244