| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 4 | NC_000004.12:g.130057834A>G |
| GRCh37.p13 chr 4 | NC_000004.11:g.130978989A>G |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | A=0.100 | G=0.900 |
| 1000Genomes | American | Sub | 694 | A=0.450 | G=0.550 |
| 1000Genomes | East Asian | Sub | 1008 | A=0.334 | G=0.666 |
| 1000Genomes | Europe | Sub | 1006 | A=0.557 | G=0.443 |
| 1000Genomes | Global | Study-wide | 5008 | A=0.382 | G=0.618 |
| 1000Genomes | South Asian | Sub | 978 | A=0.590 | G=0.410 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | A=0.546 | G=0.454 |
| The Genome Aggregation Database | African | Sub | 8708 | A=0.164 | G=0.836 |
| The Genome Aggregation Database | American | Sub | 836 | A=0.450 | G=0.550 |
| The Genome Aggregation Database | East Asian | Sub | 1608 | A=0.349 | G=0.651 |
| The Genome Aggregation Database | Europe | Sub | 18444 | A=0.557 | G=0.442 |
| The Genome Aggregation Database | Global | Study-wide | 29898 | A=0.428 | G=0.571 |
| The Genome Aggregation Database | Other | Sub | 302 | A=0.550 | G=0.450 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | A=0.374 | G=0.625 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | A=0.561 | G=0.439 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 24277619 | ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample. | Quillen EE | Am J Med Genet B Neuropsychiatr Genet |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs6534762 | 2.9E-05 | alcohol dependence | 24277619 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue | |
|---|---|---|---|---|---|---|---|
| There is no eQTL annotation for this SNP | |||||||
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr4 | 131020256 | 131020564 | E068 | 41267 |
| chr4 | 130931090 | 130931253 | E072 | -47736 |
| chr4 | 130931640 | 130931727 | E072 | -47262 |
| chr4 | 131008582 | 131008684 | E081 | 29593 |
| chr4 | 131008889 | 131009244 | E081 | 29900 |