rs6549184

Homo sapiens
G>A
ARL6IP5 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0128 (3839/29896,GnomAD)
A=0150 (4385/29118,TOPMED)
A=0194 (973/5008,1000G)
A=0043 (166/3854,ALSPAC)
A=0034 (125/3708,TWINSUK)
chr3:69101126 (GRCh38.p7) (3p14.1)
AD
GWASdb2
1   publication(s)
See rs on genome
231 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.69101126G>A
GRCh37.p13 chr 3NC_000003.11:g.69150277G>A

Gene: ARL6IP5, ADP ribosylation factor like GTPase 6 interacting protein 5(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ARL6IP5 transcriptNM_006407.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.709A=0.291
1000GenomesAmericanSub694G=0.950A=0.050
1000GenomesEast AsianSub1008G=0.655A=0.345
1000GenomesEuropeSub1006G=0.959A=0.041
1000GenomesGlobalStudy-wide5008G=0.806A=0.194
1000GenomesSouth AsianSub978G=0.830A=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.957A=0.043
The Genome Aggregation DatabaseAfricanSub8686G=0.729A=0.271
The Genome Aggregation DatabaseAmericanSub838G=0.950A=0.050
The Genome Aggregation DatabaseEast AsianSub1602G=0.624A=0.376
The Genome Aggregation DatabaseEuropeSub18468G=0.955A=0.044
The Genome Aggregation DatabaseGlobalStudy-wide29896G=0.871A=0.128
The Genome Aggregation DatabaseOtherSub302G=0.950A=0.050
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.849A=0.150
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.966A=0.034
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs65491840.00011alcohol dependence20201924

eQTL of rs6549184 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6549184 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr36912738569127486E067-22791
chr36912792369128060E067-22217
chr36913027869130347E067-19930
chr36913065269130719E067-19558
chr36913075569131011E067-19266
chr36913107269131443E067-18834
chr36913162669131705E067-18572
chr36913173369131900E067-18377
chr36913195369132343E067-17934
chr36913236769132485E067-17792
chr36913253169132581E067-17696
chr36913258569132682E067-17595
chr36913274969132802E067-17475
chr36913292869132989E067-17288
chr36913794669138024E067-12253
chr36913810269138203E067-12074
chr36913896569139651E067-10626
chr36914027269140345E067-9932
chr36914054569140731E067-9546
chr36914076969141701E067-8576
chr36914176369141820E067-8457
chr36914197769142112E067-8165
chr36914236969142439E067-7838
chr36914247969142531E067-7746
chr36914276569142881E067-7396
chr36914294469143193E067-7084
chr36914401669144279E067-5998
chr36914492469145157E067-5120
chr36914528669145380E067-4897
chr36914563369145697E067-4580
chr36914663069147171E067-3106
chr36914995069150048E067-229
chr36915012669150166E067-111
chr36915344769153497E0673170
chr36915362169153869E0673344
chr36915388669153993E0673609
chr36916235869162410E06712081
chr36916266869163126E06712391
chr36912738569127486E068-22791
chr36912792369128060E068-22217
chr36913195369132343E068-17934
chr36913236769132485E068-17792
chr36913253169132581E068-17696
chr36913258569132682E068-17595
chr36913274969132802E068-17475
chr36913292869132989E068-17288
chr36913810269138203E068-12074
chr36913896569139651E068-10626
chr36914027269140345E068-9932
chr36914054569140731E068-9546
chr36914197769142112E068-8165
chr36914236969142439E068-7838
chr36914247969142531E068-7746
chr36914276569142881E068-7396
chr36914294469143193E068-7084
chr36914401669144279E068-5998
chr36914492469145157E068-5120
chr36914528669145380E068-4897
chr36914563369145697E068-4580
chr36914879769148908E068-1369
chr36914895969149079E068-1198
chr36919406869194410E06843791
chr36912792369128060E069-22217
chr36913195369132343E069-17934
chr36913236769132485E069-17792
chr36913253169132581E069-17696
chr36913258569132682E069-17595
chr36913274969132802E069-17475
chr36913292869132989E069-17288
chr36913794669138024E069-12253
chr36913810269138203E069-12074
chr36913896569139651E069-10626
chr36914027269140345E069-9932
chr36914054569140731E069-9546
chr36914076969141701E069-8576
chr36914176369141820E069-8457
chr36914197769142112E069-8165
chr36914236969142439E069-7838
chr36914247969142531E069-7746
chr36914276569142881E069-7396
chr36914294469143193E069-7084
chr36914401669144279E069-5998
chr36914492469145157E069-5120
chr36914528669145380E069-4897
chr36914563369145697E069-4580
chr36914663069147171E069-3106
chr36914879769148908E069-1369
chr36914895969149079E069-1198
chr36916235869162410E06912081
chr36916266869163126E06912391
chr36910227669102347E070-47930
chr36912738569127486E070-22791
chr36912792369128060E070-22217
chr36913794669138024E070-12253
chr36914176369141820E070-8457
chr36914320669143377E070-6900
chr36914339469143937E070-6340
chr36912738569127486E071-22791
chr36912792369128060E071-22217
chr36913027869130347E071-19930
chr36913065269130719E071-19558
chr36913075569131011E071-19266
chr36913107269131443E071-18834
chr36913258569132682E071-17595
chr36913274969132802E071-17475
chr36913292869132989E071-17288
chr36913896569139651E071-10626
chr36914027269140345E071-9932
chr36914054569140731E071-9546
chr36914197769142112E071-8165
chr36914236969142439E071-7838
chr36914247969142531E071-7746
chr36914276569142881E071-7396
chr36914294469143193E071-7084
chr36914339469143937E071-6340
chr36914401669144279E071-5998
chr36914492469145157E071-5120
chr36914528669145380E071-4897
chr36914563369145697E071-4580
chr36914663069147171E071-3106
chr36914879769148908E071-1369
chr36914895969149079E071-1198
chr36915344769153497E0713170
chr36915362169153869E0713344
chr36915388669153993E0713609
chr36915425569154462E0713978
chr36915450769154571E0714230
chr36915457969154709E0714302
chr36915510769155210E0714830
chr36915523169155291E0714954
chr36915535969155409E0715082
chr36915567469155724E0715397
chr36916235869162410E07112081
chr36916266869163126E07112391
chr36916321169163522E07112934
chr36916491269165207E07114635
chr36916776769167817E07117490
chr36912792369128060E072-22217
chr36913027869130347E072-19930
chr36913065269130719E072-19558
chr36913075569131011E072-19266
chr36913810269138203E072-12074
chr36913896569139651E072-10626
chr36914027269140345E072-9932
chr36914054569140731E072-9546
chr36914076969141701E072-8576
chr36914176369141820E072-8457
chr36914197769142112E072-8165
chr36914236969142439E072-7838
chr36914247969142531E072-7746
chr36914276569142881E072-7396
chr36914294469143193E072-7084
chr36914320669143377E072-6900
chr36914339469143937E072-6340
chr36914401669144279E072-5998
chr36914492469145157E072-5120
chr36914528669145380E072-4897
chr36914563369145697E072-4580
chr36914663069147171E072-3106
chr36914879769148908E072-1369
chr36914895969149079E072-1198
chr36919406869194410E07243791
chr36912792369128060E073-22217
chr36913810269138203E073-12074
chr36913896569139651E073-10626
chr36914027269140345E073-9932
chr36914054569140731E073-9546
chr36914076969141701E073-8576
chr36914176369141820E073-8457
chr36914197769142112E073-8165
chr36914236969142439E073-7838
chr36914247969142531E073-7746
chr36914276569142881E073-7396
chr36914294469143193E073-7084
chr36914339469143937E073-6340
chr36914401669144279E073-5998
chr36914492469145157E073-5120
chr36914528669145380E073-4897
chr36914879769148908E073-1369
chr36914895969149079E073-1198
chr36912792369128060E074-22217
chr36913027869130347E074-19930
chr36913065269130719E074-19558
chr36913075569131011E074-19266
chr36913107269131443E074-18834
chr36913162669131705E074-18572
chr36913173369131900E074-18377
chr36913195369132343E074-17934
chr36913236769132485E074-17792
chr36913253169132581E074-17696
chr36913258569132682E074-17595
chr36913274969132802E074-17475
chr36913292869132989E074-17288
chr36914027269140345E074-9932
chr36914054569140731E074-9546
chr36914076969141701E074-8576
chr36914176369141820E074-8457
chr36914197769142112E074-8165
chr36914236969142439E074-7838
chr36914247969142531E074-7746
chr36914276569142881E074-7396
chr36914294469143193E074-7084
chr36914339469143937E074-6340
chr36914401669144279E074-5998
chr36914492469145157E074-5120
chr36914528669145380E074-4897
chr36914563369145697E074-4580
chr36914663069147171E074-3106
chr36914879769148908E074-1369
chr36914895969149079E074-1198
chr36914995069150048E074-229
chr36915012669150166E074-111
chr36915344769153497E0743170
chr36915362169153869E0743344
chr36915388669153993E0743609
chr36915510769155210E0744830
chr36915523169155291E0744954
chr36915535969155409E0745082
chr36916266869163126E07412391
chr36916321169163522E07412934
chr36916491269165207E07414635
chr36916606069166370E07415783
chr36919406869194410E07443791
chr36919499469195065E07444717
chr36912738569127486E081-22791
chr36912792369128060E081-22217
chr36913292869132989E081-17288
chr36910227669102347E082-47930
chr36914076969141701E082-8576
chr36914176369141820E082-8457
chr36914197769142112E082-8165










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr36912821269130091E067-20186
chr36913317869136002E067-14275
chr36912821269130091E068-20186
chr36913317869136002E068-14275
chr36912821269130091E069-20186
chr36913317869136002E069-14275
chr36912821269130091E070-20186
chr36913317869136002E070-14275
chr36912821269130091E071-20186
chr36913317869136002E071-14275
chr36912821269130091E072-20186
chr36913317869136002E072-14275
chr36912821269130091E073-20186
chr36913317869136002E073-14275
chr36912821269130091E074-20186
chr36913317869136002E074-14275
chr36912821269130091E081-20186
chr36913317869136002E081-14275
chr36912821269130091E082-20186
chr36913317869136002E082-14275