rs656208

Homo sapiens
C>G / C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0331 (9656/29118,TOPMED)
T=0323 (7525/23262,GnomAD)
T=0402 (2014/5008,1000G)
T=0196 (754/3854,ALSPAC)
T=0198 (734/3708,TWINSUK)
chr5:14105739 (GRCh38.p7) (5p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.14105739C>G
GRCh38.p7 chr 5NC_000005.10:g.14105739C>T
GRCh37.p13 chr 5NC_000005.9:g.14105848C>G
GRCh37.p13 chr 5NC_000005.9:g.14105848C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.483T=0.517
1000GenomesAmericanSub694C=0.730T=0.270
1000GenomesEast AsianSub1008C=0.440T=0.560
1000GenomesEuropeSub1006C=0.796T=0.204
1000GenomesGlobalStudy-wide5008C=0.598T=0.402
1000GenomesSouth AsianSub978C=0.620T=0.380
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.804T=0.196
The Genome Aggregation DatabaseAfricanSub7178C=0.528T=0.472
The Genome Aggregation DatabaseAmericanSub590C=0.750T=0.25,
The Genome Aggregation DatabaseEast AsianSub1434C=0.422T=0.578
The Genome Aggregation DatabaseEuropeSub13782C=0.775T=0.224
The Genome Aggregation DatabaseGlobalStudy-wide23262C=0.676T=0.323
The Genome Aggregation DatabaseOtherSub278C=0.780T=0.22,
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.668T=0.331
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.802T=0.198
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs6562088.39E-05alcohol consumption23743675

eQTL of rs656208 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs656208 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr579109657911038E072-46915