rs6565917

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0098 (2944/29948,GnomAD)
A==0119 (3478/29118,TOPMED)
A==0112 (561/5008,1000G)
A==0064 (248/3854,ALSPAC)
A==0069 (256/3708,TWINSUK)
chr18:76779719 (GRCh38.p7) (18q23)
AD
GWASdb2
1   publication(s)
See rs on genome
40 Enhancers around
22 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.76779719A>G
GRCh37.p13 chr 18NC_000018.9:g.74491675A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.151G=0.849
1000GenomesAmericanSub694A=0.080G=0.920
1000GenomesEast AsianSub1008A=0.119G=0.881
1000GenomesEuropeSub1006A=0.081G=0.919
1000GenomesGlobalStudy-wide5008A=0.112G=0.888
1000GenomesSouth AsianSub978A=0.110G=0.890
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.064G=0.936
The Genome Aggregation DatabaseAfricanSub8708A=0.145G=0.855
The Genome Aggregation DatabaseAmericanSub838A=0.050G=0.950
The Genome Aggregation DatabaseEast AsianSub1618A=0.098G=0.902
The Genome Aggregation DatabaseEuropeSub18482A=0.078G=0.921
The Genome Aggregation DatabaseGlobalStudy-wide29948A=0.098G=0.901
The Genome Aggregation DatabaseOtherSub302A=0.120G=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.119G=0.880
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.069G=0.931
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs65659170.00067alcohol dependence20201924

eQTL of rs6565917 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6565917 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr187451564474516123E06723969
chr187453674574536798E06745070
chr187453681174536965E06745136
chr187453697274537312E06745297
chr187453739474537492E06745719
chr187444807074448192E068-43483
chr187444819874448288E068-43387
chr187445187074451922E068-39753
chr187445198174452247E068-39428
chr187447468974474746E068-16929
chr187448316774484370E068-7305
chr187444807074448192E069-43483
chr187444819874448288E069-43387
chr187448281174483015E069-8660
chr187448316774484370E069-7305
chr187451564474516123E06923969
chr187447625174476662E070-15013
chr187453674574536798E07045070
chr187448281174483015E071-8660
chr187451564474516123E07223969
chr187451699374517073E07225318
chr187451724174517451E07225566
chr187453228774532393E07240612
chr187451549474515534E07323819
chr187453674574536798E07345070
chr187453681174536965E07345136
chr187453697274537312E07345297
chr187444854474448584E074-43091
chr187447625174476662E081-15013
chr187453156374531655E08139888
chr187453210074532140E08140425
chr187453228774532393E08140612
chr187453674574536798E08145070
chr187453681174536965E08145136
chr187447625174476662E082-15013
chr187451549474515534E08223819
chr187451564474516123E08223969
chr187453228774532393E08240612
chr187453674574536798E08245070
chr187453681174536965E08245136










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr187451364374514484E06721968
chr187453279074536641E06741115
chr187449945974499794E0687784
chr187449981174499980E0688136
chr187451364374514484E06821968
chr187453279074536641E06841115
chr187451364374514484E06921968
chr187453279074536641E06941115
chr187449945974499794E0707784
chr187453279074536641E07041115
chr187451364374514484E07121968
chr187453279074536641E07141115
chr187451364374514484E07221968
chr187453279074536641E07241115
chr187451364374514484E07321968
chr187453279074536641E07341115
chr187451364374514484E07421968
chr187453279074536641E07441115
chr187449945974499794E0827784
chr187449981174499980E0828136
chr187451364374514484E08221968
chr187453279074536641E08241115