rs6565917

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0098 (2944/29948,GnomAD)
A==0119 (3478/29118,TOPMED)
A==0112 (561/5008,1000G)
A==0064 (248/3854,ALSPAC)
A==0069 (256/3708,TWINSUK)

Position: chr18:76779719 (GRCh38.p7) (18q23)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 40 Enhancers around

Promoter: 22 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 18	NC_000018.10:g.76779719A>G
GRCh37.p13 chr 18	NC_000018.9:g.74491675A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.151	G=0.849
1000Genomes	American	Sub	694	A=0.080	G=0.920
1000Genomes	East Asian	Sub	1008	A=0.119	G=0.881
1000Genomes	Europe	Sub	1006	A=0.081	G=0.919
1000Genomes	Global	Study-wide	5008	A=0.112	G=0.888
1000Genomes	South Asian	Sub	978	A=0.110	G=0.890
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.064	G=0.936
The Genome Aggregation Database	African	Sub	8708	A=0.145	G=0.855
The Genome Aggregation Database	American	Sub	838	A=0.050	G=0.950
The Genome Aggregation Database	East Asian	Sub	1618	A=0.098	G=0.902
The Genome Aggregation Database	Europe	Sub	18482	A=0.078	G=0.921
The Genome Aggregation Database	Global	Study-wide	29948	A=0.098	G=0.901
The Genome Aggregation Database	Other	Sub	302	A=0.120	G=0.880
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.119	G=0.880
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.069	G=0.931

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6565917	0.00067	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

There is no significant Hi-C chromatin interaction data for this SNP.

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr18	74515644	74516123	E067	23969
chr18	74536745	74536798	E067	45070
chr18	74536811	74536965	E067	45136
chr18	74536972	74537312	E067	45297
chr18	74537394	74537492	E067	45719
chr18	74448070	74448192	E068	-43483
chr18	74448198	74448288	E068	-43387
chr18	74451870	74451922	E068	-39753
chr18	74451981	74452247	E068	-39428
chr18	74474689	74474746	E068	-16929
chr18	74483167	74484370	E068	-7305
chr18	74448070	74448192	E069	-43483
chr18	74448198	74448288	E069	-43387
chr18	74482811	74483015	E069	-8660
chr18	74483167	74484370	E069	-7305
chr18	74515644	74516123	E069	23969
chr18	74476251	74476662	E070	-15013
chr18	74536745	74536798	E070	45070
chr18	74482811	74483015	E071	-8660
chr18	74515644	74516123	E072	23969
chr18	74516993	74517073	E072	25318
chr18	74517241	74517451	E072	25566
chr18	74532287	74532393	E072	40612
chr18	74515494	74515534	E073	23819
chr18	74536745	74536798	E073	45070
chr18	74536811	74536965	E073	45136
chr18	74536972	74537312	E073	45297
chr18	74448544	74448584	E074	-43091
chr18	74476251	74476662	E081	-15013
chr18	74531563	74531655	E081	39888
chr18	74532100	74532140	E081	40425
chr18	74532287	74532393	E081	40612
chr18	74536745	74536798	E081	45070
chr18	74536811	74536965	E081	45136
chr18	74476251	74476662	E082	-15013
chr18	74515494	74515534	E082	23819
chr18	74515644	74516123	E082	23969
chr18	74532287	74532393	E082	40612
chr18	74536745	74536798	E082	45070
chr18	74536811	74536965	E082	45136

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr18	74513643	74514484	E067	21968
chr18	74532790	74536641	E067	41115
chr18	74499459	74499794	E068	7784
chr18	74499811	74499980	E068	8136
chr18	74513643	74514484	E068	21968
chr18	74532790	74536641	E068	41115
chr18	74513643	74514484	E069	21968
chr18	74532790	74536641	E069	41115
chr18	74499459	74499794	E070	7784
chr18	74532790	74536641	E070	41115
chr18	74513643	74514484	E071	21968
chr18	74532790	74536641	E071	41115
chr18	74513643	74514484	E072	21968
chr18	74532790	74536641	E072	41115
chr18	74513643	74514484	E073	21968
chr18	74532790	74536641	E073	41115
chr18	74513643	74514484	E074	21968
chr18	74532790	74536641	E074	41115
chr18	74499459	74499794	E082	7784
chr18	74499811	74499980	E082	8136
chr18	74513643	74514484	E082	21968
chr18	74532790	74536641	E082	41115