rs6573135

Homo sapiens
G>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0318 (9462/29702,GnomAD)
C=0422 (12314/29118,TOPMED)
C=0326 (1635/5008,1000G)
C=0135 (521/3854,ALSPAC)
C=0150 (557/3708,TWINSUK)
chr14:57197656 (GRCh38.p7) (14q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.57197656G>C
GRCh37.p13 chr 14NC_000014.8:g.57664374G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.098C=0.902
1000GenomesAmericanSub694G=0.870C=0.130
1000GenomesEast AsianSub1008G=0.886C=0.114
1000GenomesEuropeSub1006G=0.882C=0.118
1000GenomesGlobalStudy-wide5008G=0.674C=0.326
1000GenomesSouth AsianSub978G=0.880C=0.120
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.865C=0.135
The Genome Aggregation DatabaseAfricanSub8704G=0.223C=0.777
The Genome Aggregation DatabaseAmericanSub830G=0.890C=0.110
The Genome Aggregation DatabaseEast AsianSub1614G=0.857C=0.143
The Genome Aggregation DatabaseEuropeSub18252G=0.872C=0.127
The Genome Aggregation DatabaseGlobalStudy-wide29702G=0.681C=0.318
The Genome Aggregation DatabaseOtherSub302G=0.850C=0.150
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.577C=0.422
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.850C=0.150
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs65731357.97E-05alcohol consumption23743675

eQTL of rs6573135 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6573135 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr145764085457640986E081-23388
chr145764112257641684E081-22690
chr145764209457642148E081-22226
chr145764228557642434E081-21940