| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 11 | NC_000011.10:g.1534014A>G |
| GRCh38.p7 chr 11 | NC_000011.10:g.1534014A>T |
| GRCh37.p13 chr 11 | NC_000011.9:g.1555244A>G |
| GRCh37.p13 chr 11 | NC_000011.9:g.1555244A>T |
| GRCh38.p7 chr 11 alt locus HSCHR11_2_CTG1_1 | NT_187657.1:g.10541A>G |
| GRCh38.p7 chr 11 alt locus HSCHR11_2_CTG1_1 | NT_187657.1:g.10541A>T |
| GRCh38.p7 chr 11 alt locus HSCHR11_1_CTG6 | NT_187584.1:g.10543G>A |
| GRCh38.p7 chr 11 alt locus HSCHR11_1_CTG6 | NT_187584.1:g.10543G>T |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | A=0.202 | G=0.798 |
| 1000Genomes | American | Sub | 694 | A=0.340 | G=0.660 |
| 1000Genomes | East Asian | Sub | 1008 | A=0.607 | G=0.393 |
| 1000Genomes | Europe | Sub | 1006 | A=0.269 | G=0.731 |
| 1000Genomes | Global | Study-wide | 5008 | A=0.335 | G=0.665 |
| 1000Genomes | South Asian | Sub | 978 | A=0.300 | G=0.700 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | A=0.279 | G=0.721 |
| The Genome Aggregation Database | African | Sub | 8668 | A=0.200 | G=0.800 |
| The Genome Aggregation Database | American | Sub | 838 | A=0.360 | G=0.640 |
| The Genome Aggregation Database | East Asian | Sub | 1610 | A=0.642 | G=0.358 |
| The Genome Aggregation Database | Europe | Sub | 18310 | A=0.269 | G=0.730 |
| The Genome Aggregation Database | Global | Study-wide | 29724 | A=0.272 | G=0.727 |
| The Genome Aggregation Database | Other | Sub | 298 | A=0.320 | G=0.680 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | A=0.238 | G=0.761 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | A=0.260 | G=0.740 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 29460428 | Genomewide Association Study of Alcohol Dependence and Related Traits in a Thai Population. | Gelernter J | Alcohol Clin Exp Res |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs6578492 | 4E-06 | response to alcohol | 29460428 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue |
|---|---|---|---|---|---|---|
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 3.2110e-25 | -37339 | Cerebellum |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 0.0000e+0 | -37339 | Frontal_Cortex_BA9 |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 4.5091e-18 | -37339 | Hypothalamus |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 0.0000e+0 | -37339 | Cortex |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 1.4398e-23 | -37339 | Cerebellar_Hemisphere |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 0.0000e+0 | -37339 | Caudate_basal_ganglia |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 2.3138e-19 | -37339 | Hippocampus |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 8.4341e-21 | -37339 | Anterior_cingulate_cortex |
| Chr11:1555244 | KRTAP5-AS1 | ENSG00000233930.3 | A>G | 1.0000e-28 | -37339 | Nucleus_accumbens_basal_ganglia |
| Probe ID | Position | Gene | beta | p-value | |||
|---|---|---|---|---|---|---|---|
| There is no meQTL annotation for this SNP | |||||||
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr11 | 40140291 | 40140371 | E067 | 1952 |
| chr11 | 40140484 | 40140682 | E067 | 2145 |
| chr11 | 40140726 | 40140945 | E067 | 2387 |
| chr11 | 40155433 | 40155530 | E067 | 17094 |
| chr11 | 40156069 | 40156119 | E067 | 17730 |
| chr11 | 40156354 | 40156423 | E067 | 18015 |
| chr11 | 40156553 | 40156637 | E067 | 18214 |
| chr11 | 40183664 | 40183853 | E067 | 45325 |
| chr11 | 40150686 | 40151163 | E068 | 12347 |
| chr11 | 40151419 | 40151469 | E068 | 13080 |
| chr11 | 40152074 | 40152263 | E068 | 13735 |
| chr11 | 40154314 | 40154368 | E068 | 15975 |
| chr11 | 40155433 | 40155530 | E068 | 17094 |
| chr11 | 40180902 | 40180967 | E068 | 42563 |
| chr11 | 40183664 | 40183853 | E068 | 45325 |
| chr11 | 40184008 | 40184089 | E068 | 45669 |
| chr11 | 40184308 | 40184579 | E068 | 45969 |
| chr11 | 40140484 | 40140682 | E069 | 2145 |
| chr11 | 40140726 | 40140945 | E069 | 2387 |
| chr11 | 40140976 | 40141050 | E069 | 2637 |
| chr11 | 40150529 | 40150604 | E069 | 12190 |
| chr11 | 40150686 | 40151163 | E069 | 12347 |
| chr11 | 40152074 | 40152263 | E069 | 13735 |
| chr11 | 40162237 | 40162365 | E069 | 23898 |
| chr11 | 40183664 | 40183853 | E069 | 45325 |
| chr11 | 40184008 | 40184089 | E069 | 45669 |
| chr11 | 40140291 | 40140371 | E071 | 1952 |
| chr11 | 40140484 | 40140682 | E071 | 2145 |
| chr11 | 40140726 | 40140945 | E071 | 2387 |
| chr11 | 40150529 | 40150604 | E071 | 12190 |
| chr11 | 40150686 | 40151163 | E071 | 12347 |
| chr11 | 40151419 | 40151469 | E071 | 13080 |
| chr11 | 40152074 | 40152263 | E071 | 13735 |
| chr11 | 40160641 | 40160924 | E071 | 22302 |
| chr11 | 40160949 | 40161288 | E071 | 22610 |
| chr11 | 40140484 | 40140682 | E072 | 2145 |
| chr11 | 40150529 | 40150604 | E072 | 12190 |
| chr11 | 40150686 | 40151163 | E072 | 12347 |
| chr11 | 40152074 | 40152263 | E072 | 13735 |
| chr11 | 40152074 | 40152263 | E073 | 13735 |
| chr11 | 40140484 | 40140682 | E074 | 2145 |
| chr11 | 40140726 | 40140945 | E074 | 2387 |
| chr11 | 40140976 | 40141050 | E074 | 2637 |
| chr11 | 40154314 | 40154368 | E074 | 15975 |
| chr11 | 40154574 | 40154637 | E074 | 16235 |
| chr11 | 40156069 | 40156119 | E074 | 17730 |
| chr11 | 40156354 | 40156423 | E074 | 18015 |
| chr11 | 40156553 | 40156637 | E074 | 18214 |
| chr11 | 40156671 | 40156812 | E074 | 18332 |
| chr11 | 40156816 | 40156970 | E074 | 18477 |
| chr11 | 40183664 | 40183853 | E074 | 45325 |
| chr11 | 40184008 | 40184089 | E074 | 45669 |
| chr11 | 40184308 | 40184579 | E074 | 45969 |
| chr11 | 40184591 | 40184721 | E074 | 46252 |
| chr11 | 40160395 | 40160607 | E081 | 22056 |
| chr11 | 40160641 | 40160924 | E081 | 22302 |