rs6583832

Homo sapiens
T>G
KIF11 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0144 (4315/29964,GnomAD)
G=0216 (6315/29118,TOPMED)
G=0178 (892/5008,1000G)
G=0041 (159/3854,ALSPAC)
G=0038 (141/3708,TWINSUK)
chr10:92641615 (GRCh38.p7) (10q23.33)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
15 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.92641615T>G
GRCh37.p13 chr 10NC_000010.10:g.94401372T>G
KIF11 RefSeqGeneNG_032580.1:g.53548T>G

Gene: KIF11, kinesin family member 11(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KIF11 transcriptNM_004523.3:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.547G=0.453
1000GenomesAmericanSub694T=0.880G=0.120
1000GenomesEast AsianSub1008T=0.913G=0.087
1000GenomesEuropeSub1006T=0.966G=0.034
1000GenomesGlobalStudy-wide5008T=0.822G=0.178
1000GenomesSouth AsianSub978T=0.910G=0.090
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.959G=0.041
The Genome Aggregation DatabaseAfricanSub8720T=0.608G=0.392
The Genome Aggregation DatabaseAmericanSub838T=0.900G=0.100
The Genome Aggregation DatabaseEast AsianSub1620T=0.881G=0.119
The Genome Aggregation DatabaseEuropeSub18484T=0.967G=0.032
The Genome Aggregation DatabaseGlobalStudy-wide29964T=0.856G=0.144
The Genome Aggregation DatabaseOtherSub302T=0.930G=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.783G=0.216
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.962G=0.038
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs65838320.000814nicotine dependence17158188

eQTL of rs6583832 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6583832 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr109435222694354210E067-47162
chr109435222694354210E068-47162
chr109435222694354210E069-47162
chr109435222694354210E070-47162
chr109435441594354540E070-46832
chr109435455594354945E070-46427
chr109435516794355256E070-46116
chr109435222694354210E071-47162
chr109435222694354210E072-47162
chr109435222694354210E073-47162
chr109435222694354210E074-47162
chr109435222694354210E081-47162
chr109435222694354210E082-47162
chr109435441594354540E082-46832
chr109435455594354945E082-46427