SNP Detail Info-rs6583832

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

KIF11 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0144 (4315/29964,GnomAD)
G=0216 (6315/29118,TOPMED)
G=0178 (892/5008,1000G)
G=0041 (159/3854,ALSPAC)
G=0038 (141/3708,TWINSUK)

Position: chr10:92641615 (GRCh38.p7) (10q23.33)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 15 Promoters around

Molecule type	Change	Amino acid[Codon]	SO Term
KIF11 transcript	NM_004523.3:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.547	G=0.453
1000Genomes	American	Sub	694	T=0.880	G=0.120
1000Genomes	East Asian	Sub	1008	T=0.913	G=0.087
1000Genomes	Europe	Sub	1006	T=0.966	G=0.034
1000Genomes	Global	Study-wide	5008	T=0.822	G=0.178
1000Genomes	South Asian	Sub	978	T=0.910	G=0.090
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.959	G=0.041
The Genome Aggregation Database	African	Sub	8720	T=0.608	G=0.392
The Genome Aggregation Database	American	Sub	838	T=0.900	G=0.100
The Genome Aggregation Database	East Asian	Sub	1620	T=0.881	G=0.119
The Genome Aggregation Database	Europe	Sub	18484	T=0.967	G=0.032
The Genome Aggregation Database	Global	Study-wide	29964	T=0.856	G=0.144
The Genome Aggregation Database	Other	Sub	302	T=0.930	G=0.070
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.783	G=0.216
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.962	G=0.038

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

SNP ID	p-value	Traits	Study
rs6583832	0.000814	nicotine dependence	17158188

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr10	94352226	94354210	E067	-47162
chr10	94352226	94354210	E068	-47162
chr10	94352226	94354210	E069	-47162
chr10	94352226	94354210	E070	-47162
chr10	94354415	94354540	E070	-46832
chr10	94354555	94354945	E070	-46427
chr10	94355167	94355256	E070	-46116
chr10	94352226	94354210	E071	-47162
chr10	94352226	94354210	E072	-47162
chr10	94352226	94354210	E073	-47162
chr10	94352226	94354210	E074	-47162
chr10	94352226	94354210	E081	-47162
chr10	94352226	94354210	E082	-47162
chr10	94354415	94354540	E082	-46832
chr10	94354555	94354945	E082	-46427

rs6583832