rs6665548

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0188 (5597/29760,GnomAD)
G=0197 (5739/29116,TOPMED)
G=0144 (719/5008,1000G)
G=0298 (1150/3854,ALSPAC)
G=0286 (1061/3708,TWINSUK)
chr1:214243481 (GRCh38.p7) (1q32.3)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.214243481A>G
GRCh37.p13 chr 1NC_000001.10:g.214416824A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.966G=0.034
1000GenomesAmericanSub694A=0.840G=0.160
1000GenomesEast AsianSub1008A=0.979G=0.021
1000GenomesEuropeSub1006A=0.716G=0.284
1000GenomesGlobalStudy-wide5008A=0.856G=0.144
1000GenomesSouth AsianSub978A=0.740G=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.702G=0.298
The Genome Aggregation DatabaseAfricanSub8650A=0.942G=0.058
The Genome Aggregation DatabaseAmericanSub834A=0.830G=0.170
The Genome Aggregation DatabaseEast AsianSub1614A=0.973G=0.027
The Genome Aggregation DatabaseEuropeSub18362A=0.738G=0.262
The Genome Aggregation DatabaseGlobalStudy-wide29760A=0.811G=0.188
The Genome Aggregation DatabaseOtherSub300A=0.640G=0.360
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.802G=0.197
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.714G=0.286
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs66655480.000604alcohol dependence21314694

eQTL of rs6665548 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6665548 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1214382313214382401E067-34423
chr1214382914214383013E067-33811
chr1214381961214382147E068-34677
chr1214382313214382401E068-34423
chr1214382914214383013E068-33811
chr1214387349214388054E068-28770
chr1214434761214435468E06817937
chr1214435576214435692E06818752
chr1214382914214383013E069-33811
chr1214401412214401519E069-15305
chr1214401637214401913E069-14911
chr1214402220214402344E069-14480
chr1214402356214402732E069-14092
chr1214435576214435692E06918752
chr1214456066214456266E06939242
chr1214381961214382147E070-34677
chr1214382313214382401E070-34423
chr1214382914214383013E070-33811
chr1214400894214401126E070-15698
chr1214401201214401257E070-15567
chr1214401412214401519E070-15305
chr1214451841214451996E07035017
chr1214452180214452452E07035356
chr1214456066214456266E07039242
chr1214456477214456714E07039653
chr1214382914214383013E071-33811
chr1214387349214388054E071-28770
chr1214401637214401913E071-14911
chr1214402220214402344E071-14480
chr1214402356214402732E071-14092
chr1214435576214435692E07118752
chr1214456066214456266E07139242
chr1214382914214383013E072-33811
chr1214456066214456266E07239242
chr1214382313214382401E073-34423
chr1214387349214388054E073-28770
chr1214434761214435468E07317937
chr1214382914214383013E074-33811
chr1214402220214402344E074-14480
chr1214402356214402732E074-14092
chr1214381961214382147E081-34677
chr1214387349214388054E081-28770
chr1214400894214401126E081-15698
chr1214401201214401257E081-15567
chr1214401412214401519E081-15305
chr1214401637214401913E081-14911
chr1214434761214435468E08117937
chr1214435576214435692E08118752
chr1214400894214401126E082-15698
chr1214401201214401257E082-15567
chr1214401412214401519E082-15305
chr1214401637214401913E082-14911
chr1214434761214435468E08217937
chr1214435576214435692E08218752
chr1214451841214451996E08235017
chr1214456066214456266E08239242
chr1214456477214456714E08239653










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1214397818214398688E067-18136
chr1214398769214398829E067-17995
chr1214453206214455908E06736382
chr1214397818214398688E068-18136
chr1214398769214398829E068-17995
chr1214453206214455908E06836382
chr1214397818214398688E069-18136
chr1214453206214455908E06936382
chr1214397818214398688E070-18136
chr1214398769214398829E070-17995
chr1214453206214455908E07036382
chr1214397818214398688E071-18136
chr1214398769214398829E071-17995
chr1214453206214455908E07136382
chr1214397818214398688E072-18136
chr1214398769214398829E072-17995
chr1214453206214455908E07236382
chr1214397818214398688E073-18136
chr1214453206214455908E07336382
chr1214397818214398688E074-18136
chr1214453206214455908E07436382
chr1214453206214455908E08136382
chr1214397818214398688E082-18136
chr1214398769214398829E082-17995
chr1214453206214455908E08236382