rs66691212

Homo sapiens
T>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0372 (11122/29866,GnomAD)
G=0283 (8243/29118,TOPMED)
G=0341 (1708/5008,1000G)
G=0444 (1713/3854,ALSPAC)
G=0467 (1731/3708,TWINSUK)
chr11:37364436 (GRCh38.p7) (11p12)
CD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.37364436T>G
GRCh37.p13 chr 11NC_000011.9:g.37385986T>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.972G=0.028
1000GenomesAmericanSub694T=0.630G=0.370
1000GenomesEast AsianSub1008T=0.431G=0.569
1000GenomesEuropeSub1006T=0.550G=0.450
1000GenomesGlobalStudy-wide5008T=0.659G=0.341
1000GenomesSouth AsianSub978T=0.600G=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.556G=0.444
The Genome Aggregation DatabaseAfricanSub8714T=0.913G=0.087
The Genome Aggregation DatabaseAmericanSub836T=0.630G=0.370
The Genome Aggregation DatabaseEast AsianSub1602T=0.432G=0.568
The Genome Aggregation DatabaseEuropeSub18412T=0.511G=0.488
The Genome Aggregation DatabaseGlobalStudy-wide29866T=0.627G=0.372
The Genome Aggregation DatabaseOtherSub302T=0.510G=0.490
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.716G=0.283
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.533G=0.467
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs666912120.000252cocaine dependence23958962
rs666912120.00085cocaine dependence,AA23958962

eQTL of rs66691212 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs66691212 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr113740086437400914E08114878
chr113740091537400993E08114929
chr113740146637401631E08115480
chr113735783037357880E082-28106


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr113734426137344426E068-41560