SNP Detail Info-rs667577

Sequence Name	Change(s)
GRCh38.p7 chr 22	NC_000022.11:g.26378614A>G
GRCh37.p13 chr 22	NC_000022.10:g.26774580A>G

Molecule type	Change	Amino acid[Codon]	SO Term
SEZ6L transcript variant 2	NM_001184773.1:c.	N/A	Intron Variant
SEZ6L transcript variant 3	NM_001184774.1:c.	N/A	Intron Variant
SEZ6L transcript variant 4	NM_001184775.1:c.	N/A	Intron Variant
SEZ6L transcript variant 5	NM_001184776.1:c.	N/A	Intron Variant
SEZ6L transcript variant 6	NM_001184777.1:c.	N/A	Intron Variant
SEZ6L transcript variant 1	NM_021115.4:c.	N/A	Intron Variant
SEZ6L transcript variant X2	XM_005261439.3:c.	N/A	Intron Variant
SEZ6L transcript variant X3	XM_005261440.3:c.	N/A	Intron Variant
SEZ6L transcript variant X1	XM_006724195.3:c.	N/A	Intron Variant
SEZ6L transcript variant X4	XM_011530037.2:c.	N/A	Intron Variant
SEZ6L transcript variant X6	XM_011530038.2:c.	N/A	Intron Variant
SEZ6L transcript variant X8	XM_011530039.2:c.	N/A	Intron Variant
SEZ6L transcript variant X5	XM_017028699.1:c.	N/A	Intron Variant
SEZ6L transcript variant X7	XM_017028700.1:c.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.331	G=0.669
1000Genomes	American	Sub	694	A=0.210	G=0.790
1000Genomes	East Asian	Sub	1008	A=0.016	G=0.984
1000Genomes	Europe	Sub	1006	A=0.309	G=0.691
1000Genomes	Global	Study-wide	5008	A=0.214	G=0.786
1000Genomes	South Asian	Sub	978	A=0.160	G=0.840
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.308	G=0.692
The Genome Aggregation Database	African	Sub	8712	A=0.332	G=0.668
The Genome Aggregation Database	American	Sub	838	A=0.230	G=0.770
The Genome Aggregation Database	East Asian	Sub	1620	A=0.017	G=0.983
The Genome Aggregation Database	Europe	Sub	18476	A=0.290	G=0.709
The Genome Aggregation Database	Global	Study-wide	29948	A=0.286	G=0.713
The Genome Aggregation Database	Other	Sub	302	A=0.360	G=0.640
Trans-Omics for Precision Medicine	Global	Study-wide	29116	A=0.312	G=0.687
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.316	G=0.684

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs667577	0.0000858	alcoholism	pha002892
rs667577	0.000086	alcohol dependence(early age of onset)	20201924
rs667577	0.00019	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr22	26756113	26756844	E067	-17736
chr22	26800850	26801386	E067	26270
chr22	26801526	26801576	E067	26946
chr22	26756113	26756844	E068	-17736
chr22	26800197	26800281	E068	25617
chr22	26800850	26801386	E068	26270
chr22	26801526	26801576	E068	26946
chr22	26756113	26756844	E069	-17736
chr22	26801526	26801576	E069	26946
chr22	26801705	26801755	E069	27125
chr22	26823939	26824014	E069	49359
chr22	26726815	26726882	E070	-47698
chr22	26756113	26756844	E070	-17736
chr22	26770316	26770965	E070	-3615
chr22	26771181	26771248	E070	-3332
chr22	26771410	26771464	E070	-3116
chr22	26794640	26795087	E071	20060
chr22	26795149	26795254	E071	20569
chr22	26800850	26801386	E071	26270
chr22	26801526	26801576	E071	26946
chr22	26823939	26824014	E071	49359
chr22	26794640	26795087	E072	20060
chr22	26795149	26795254	E072	20569
chr22	26800850	26801386	E072	26270
chr22	26800094	26800178	E073	25514
chr22	26800197	26800281	E073	25617
chr22	26800850	26801386	E073	26270
chr22	26801526	26801576	E073	26946
chr22	26801705	26801755	E073	27125
chr22	26756113	26756844	E074	-17736
chr22	26777054	26777152	E081	2474
chr22	26777466	26777506	E081	2886
chr22	26777548	26777598	E081	2968
chr22	26786548	26786604	E081	11968
chr22	26786634	26786712	E081	12054
chr22	26786956	26787333	E081	12376
chr22	26787662	26787962	E081	13082
chr22	26805760	26806713	E081	31180
chr22	26823939	26824014	E081	49359
chr22	26760366	26760818	E082	-13762
chr22	26760887	26760967	E082	-13613
chr22	26786548	26786604	E082	11968
chr22	26786634	26786712	E082	12054
chr22	26800850	26801386	E082	26270
chr22	26801526	26801576	E082	26946
chr22	26805760	26806713	E082	31180

rs667577