SNP Detail Info-rs6706771

Organism: Homo sapiens

Alleles: G>A / G>T

Gene : Feature

SLC39A10 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0281 (8426/29894,GnomAD)
G==0291 (8500/29118,TOPMED)
G==0328 (1641/5008,1000G)
G==0255 (984/3854,ALSPAC)
G==0244 (903/3708,TWINSUK)

Position: chr2:195700517 (GRCh38.p7) (2q32.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 27 Enhancers around

Promoter: 10 Promoters around

Molecule type	Change	Amino acid[Codon]	SO Term
SLC39A10 transcript variant 1	NM_001127257.1:c.	N/A	Intron Variant
SLC39A10 transcript variant 2	NM_020342.2:c.	N/A	Intron Variant
SLC39A10 transcript variant X1	XM_005246689.4:c.	N/A	Intron Variant
SLC39A10 transcript variant X2	XM_011511504.2:c.	N/A	Intron Variant
SLC39A10 transcript variant X4	XM_011511505.2:c.	N/A	Intron Variant
SLC39A10 transcript variant X3	XM_011511506.2:c.	N/A	Intron Variant
SLC39A10 transcript variant X5	XM_011511507.2:c.	N/A	Intron Variant
SLC39A10 transcript variant X6	XM_017004522.1:c.	N/A	Intron Variant
SLC39A10 transcript variant X7	XM_017004523.1:c.	N/A	Genic Downstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.264	T=0.736
1000Genomes	American	Sub	694	G=0.380	T=0.620
1000Genomes	East Asian	Sub	1008	G=0.331	T=0.669
1000Genomes	Europe	Sub	1006	G=0.265	T=0.735
1000Genomes	Global	Study-wide	5008	G=0.328	T=0.672
1000Genomes	South Asian	Sub	978	G=0.430	T=0.570
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.255	T=0.745
The Genome Aggregation Database	African	Sub	8708	G=0.274	T=0.725
The Genome Aggregation Database	American	Sub	834	G=0.360	T=0.64,
The Genome Aggregation Database	East Asian	Sub	1606	G=0.366	T=0.634
The Genome Aggregation Database	Europe	Sub	18444	G=0.272	T=0.727
The Genome Aggregation Database	Global	Study-wide	29894	G=0.281	T=0.717
The Genome Aggregation Database	Other	Sub	302	G=0.430	T=0.57,
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.291	T=0.708
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.244	T=0.756

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6706771	0.00019	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
Chr2:196565241	SLC39A10	ENSG00000196950.9	G>T	9.2991e-9	124540	Cerebellum

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	196530924	196531064	E067	-5441
chr2	196531147	196531249	E067	-5256
chr2	196552291	196552796	E067	15786
chr2	196571743	196571934	E067	35238
chr2	196531147	196531249	E068	-5256
chr2	196551759	196551919	E068	15254
chr2	196552291	196552796	E068	15786
chr2	196532763	196532990	E069	-3515
chr2	196530924	196531064	E070	-5441
chr2	196531147	196531249	E070	-5256
chr2	196551398	196551453	E070	14893
chr2	196551579	196551657	E070	15074
chr2	196551759	196551919	E070	15254
chr2	196552291	196552796	E070	15786
chr2	196532763	196532990	E071	-3515
chr2	196552291	196552796	E071	15786
chr2	196530924	196531064	E073	-5441
chr2	196531147	196531249	E073	-5256
chr2	196530924	196531064	E074	-5441
chr2	196531147	196531249	E074	-5256
chr2	196526812	196526862	E081	-9643
chr2	196527010	196527154	E081	-9351
chr2	196527701	196527853	E081	-8652
chr2	196527862	196528001	E081	-8504
chr2	196528041	196528150	E081	-8355
chr2	196531147	196531249	E081	-5256
chr2	196552291	196552796	E082	15786

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr2	196520779	196524508	E067	-11997
chr2	196520779	196524508	E068	-11997
chr2	196520779	196524508	E069	-11997
chr2	196520779	196524508	E070	-11997
chr2	196520779	196524508	E071	-11997
chr2	196520779	196524508	E072	-11997
chr2	196520779	196524508	E073	-11997
chr2	196520779	196524508	E074	-11997
chr2	196520779	196524508	E081	-11997
chr2	196520779	196524508	E082	-11997

rs6706771