rs670821

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0260 (7759/29840,GnomAD)
T=0277 (8070/29118,TOPMED)
T=0220 (1101/5008,1000G)
T=0248 (954/3854,ALSPAC)
T=0249 (925/3708,TWINSUK)
chr13:21730077 (GRCh38.p7) (13q12.11)
AD
GWASdb2
1   publication(s)
See rs on genome
22 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.21730077C>T
GRCh37.p13 chr 13NC_000013.10:g.22304216C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.664T=0.336
1000GenomesAmericanSub694C=0.840T=0.160
1000GenomesEast AsianSub1008C=0.854T=0.146
1000GenomesEuropeSub1006C=0.758T=0.242
1000GenomesGlobalStudy-wide5008C=0.780T=0.220
1000GenomesSouth AsianSub978C=0.840T=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.752T=0.248
The Genome Aggregation DatabaseAfricanSub8676C=0.695T=0.305
The Genome Aggregation DatabaseAmericanSub836C=0.860T=0.140
The Genome Aggregation DatabaseEast AsianSub1620C=0.838T=0.162
The Genome Aggregation DatabaseEuropeSub18406C=0.747T=0.252
The Genome Aggregation DatabaseGlobalStudy-wide29840C=0.740T=0.260
The Genome Aggregation DatabaseOtherSub302C=0.710T=0.290
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.722T=0.277
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.751T=0.249
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs6708219E-05alcoholism (heaviness of drinking)21529783

eQTL of rs670821 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs670821 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr132231078422310860E0676568
chr132231078422310860E0686568
chr132231078422310860E0696568
chr132231097922311147E0696763
chr132230965522309720E0705439
chr132231078422310860E0706568
chr132231097922311147E0706763
chr132231118022311386E0706964
chr132231273422312837E0708518
chr132231285922312909E0708643
chr132231293422313143E0708718
chr132231319322313253E0708977
chr132231078422310860E0726568
chr132231097922311147E0726763
chr132230965522309720E0745439
chr132227562222275928E081-28288
chr132230965522309720E0815439
chr132230977122310701E0815555
chr132231078422310860E0816568
chr132231097922311147E0816763
chr132231118022311386E0816964
chr132231078422310860E0826568