rs6716455

Homo sapiens
G>A
LOC105373684 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0111 (3354/29966,GnomAD)
A=0094 (2741/29118,TOPMED)
A=0117 (584/5008,1000G)
A=0130 (500/3854,ALSPAC)
A=0133 (495/3708,TWINSUK)
chr2:150269889 (GRCh38.p7) (2q23.3)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.150269889G>A
GRCh37.p13 chr 2NC_000002.11:g.151126403G>A

Gene: LOC105373684, uncharacterized LOC105373684(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LINC01818 transcript variant X1XR_923469.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.983A=0.017
1000GenomesAmericanSub694G=0.860A=0.140
1000GenomesEast AsianSub1008G=0.823A=0.177
1000GenomesEuropeSub1006G=0.843A=0.157
1000GenomesGlobalStudy-wide5008G=0.883A=0.117
1000GenomesSouth AsianSub978G=0.870A=0.130
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.870A=0.130
The Genome Aggregation DatabaseAfricanSub8732G=0.961A=0.039
The Genome Aggregation DatabaseAmericanSub836G=0.890A=0.110
The Genome Aggregation DatabaseEast AsianSub1614G=0.794A=0.206
The Genome Aggregation DatabaseEuropeSub18482G=0.863A=0.136
The Genome Aggregation DatabaseGlobalStudy-wide29966G=0.888A=0.111
The Genome Aggregation DatabaseOtherSub302G=0.820A=0.180
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.905A=0.094
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.867A=0.133
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs67164550.0000007alcoholism (alcohol use disorder factor score)21529783
rs67164550.000009alcohol dependence21529783
rs6716455

eQTL of rs6716455 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6716455 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2151091207151091247E068-35156
chr2151091285151092080E068-34323
chr2151153160151153870E06826757
chr2151153925151153975E06827522
chr2151091207151091247E069-35156
chr2151091285151092080E069-34323
chr2151151864151152268E06925461
chr2151078948151079224E070-47179
chr2151079408151079495E070-46908
chr2151079543151079691E070-46712
chr2151085053151085103E070-41300
chr2151085518151085788E070-40615
chr2151086291151086407E070-39996
chr2151088085151088297E070-38106
chr2151088846151089767E070-36636
chr2151112209151112376E070-14027
chr2151112638151112741E070-13662
chr2151112754151112854E070-13549
chr2151113181151113283E070-13120
chr2151113285151113342E070-13061
chr2151113424151113513E070-12890
chr2151114864151114957E070-11446
chr2151116274151116727E070-9676
chr2151117340151117626E070-8777
chr2151140800151140871E07014397
chr2151143082151143207E07016679
chr2151143355151143958E07016952
chr2151152600151152790E07026197
chr2151152801151153003E07026398
chr2151153160151153870E07026757
chr2151153925151153975E07027522
chr2151091207151091247E071-35156
chr2151091285151092080E071-34323
chr2151153160151153870E07126757
chr2151153925151153975E07127522
chr2151091207151091247E072-35156
chr2151091285151092080E072-34323
chr2151153160151153870E07226757
chr2151153925151153975E07227522
chr2151153160151153870E07426757
chr2151153925151153975E07427522
chr2151091207151091247E081-35156
chr2151091285151092080E081-34323
chr2151114864151114957E081-11446
chr2151116274151116727E081-9676
chr2151153160151153870E08126757
chr2151153925151153975E08127522
chr2151155261151155358E08128858
chr2151155536151155704E08129133
chr2151078948151079224E082-47179
chr2151079408151079495E082-46908
chr2151079543151079691E082-46712
chr2151082329151082633E082-43770
chr2151091285151092080E082-34323
chr2151143355151143958E08216952
chr2151153160151153870E08226757
chr2151153925151153975E08227522