rs6726264

Homo sapiens
T>C
LOC105373402 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0465 (13880/29814,GnomAD)
T==0498 (14519/29116,TOPMED)
C=0364 (1822/5008,1000G)
C=0478 (1843/3854,ALSPAC)
C=0484 (1795/3708,TWINSUK)
chr2:6411741 (GRCh38.p7) (2p25.2)
AD
GWASdb2
1   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.6411741T>C
GRCh37.p13 chr 2NC_000002.11:g.6551873T>C

Gene: LOC105373402, uncharacterized LOC105373402(minus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105373402 transcriptXR_922743.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.440C=0.560
1000GenomesAmericanSub694T=0.680C=0.320
1000GenomesEast AsianSub1008T=0.835C=0.165
1000GenomesEuropeSub1006T=0.513C=0.487
1000GenomesGlobalStudy-wide5008T=0.636C=0.364
1000GenomesSouth AsianSub978T=0.790C=0.210
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.522C=0.478
The Genome Aggregation DatabaseAfricanSub8658T=0.433C=0.567
The Genome Aggregation DatabaseAmericanSub838T=0.680C=0.320
The Genome Aggregation DatabaseEast AsianSub1618T=0.831C=0.169
The Genome Aggregation DatabaseEuropeSub18398T=0.547C=0.452
The Genome Aggregation DatabaseGlobalStudy-wide29814T=0.534C=0.465
The Genome Aggregation DatabaseOtherSub302T=0.680C=0.320
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.498C=0.501
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.516C=0.484
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs67262640.00059alcohol dependence20201924

eQTL of rs6726264 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6726264 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr265825506582644E07030677
chr265827566583006E07030883
chr265831926583522E07031319
chr265836956583797E07031822
chr265110126511120E071-40753
chr265110126511120E074-40753
chr265890266589115E07437153
chr265891546589271E07437281
chr265894026589466E07437529
chr265896166589782E07437743
chr265638266564093E08111953
chr265642166564384E08112343
chr265645436564611E08112670
chr265613786561428E0829505
chr265638266564093E08211953
chr265642166564384E08212343
chr265896166589782E08237743
chr265900096590295E08238136