SNP Detail Info-rs6739653

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G==0153 (4611/29980,GnomAD)
G==0146 (4276/29116,TOPMED)
G==0090 (450/5008,1000G)
G==0206 (795/3854,ALSPAC)
G==0216 (801/3708,TWINSUK)

Position: chr2:6382201 (GRCh38.p7) (2p25.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 21 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.6382201G>A
GRCh37.p13 chr 2	NC_000002.11:g.6522333G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.098	A=0.902
1000Genomes	American	Sub	694	G=0.080	A=0.920
1000Genomes	East Asian	Sub	1008	G=0.005	A=0.995
1000Genomes	Europe	Sub	1006	G=0.198	A=0.802
1000Genomes	Global	Study-wide	5008	G=0.090	A=0.910
1000Genomes	South Asian	Sub	978	G=0.060	A=0.940
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.206	A=0.794
The Genome Aggregation Database	African	Sub	8732	G=0.116	A=0.884
The Genome Aggregation Database	American	Sub	836	G=0.080	A=0.920
The Genome Aggregation Database	East Asian	Sub	1620	G=0.012	A=0.988
The Genome Aggregation Database	Europe	Sub	18492	G=0.188	A=0.811
The Genome Aggregation Database	Global	Study-wide	29980	G=0.153	A=0.846
The Genome Aggregation Database	Other	Sub	300	G=0.070	A=0.930
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.146	A=0.853
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.216	A=0.784

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6739653	0.00078	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	6477567	6477816	E070	-44517
chr2	6485702	6485984	E070	-36349
chr2	6498762	6498967	E070	-23366
chr2	6499303	6499384	E070	-22949
chr2	6499608	6499855	E070	-22478
chr2	6500173	6500333	E070	-22000
chr2	6511012	6511120	E071	-11213
chr2	6511012	6511120	E074	-11213
chr2	6498762	6498967	E081	-23366
chr2	6499303	6499384	E081	-22949
chr2	6499608	6499855	E081	-22478
chr2	6500173	6500333	E081	-22000
chr2	6563826	6564093	E081	41493
chr2	6564216	6564384	E081	41883
chr2	6564543	6564611	E081	42210
chr2	6498510	6498603	E082	-23730
chr2	6498762	6498967	E082	-23366
chr2	6499303	6499384	E082	-22949
chr2	6561378	6561428	E082	39045
chr2	6563826	6564093	E082	41493
chr2	6564216	6564384	E082	41883

rs6739653