rs6740249

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0386 (11546/29870,GnomAD)
T==0314 (9149/29116,TOPMED)
T==0291 (1457/5008,1000G)
T==0477 (1840/3854,ALSPAC)
T==0487 (1806/3708,TWINSUK)
chr2:355800 (GRCh38.p7) (2p25.3)
AD
GWASdb2
1   publication(s)
See rs on genome
47 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.355800T>C
GRCh37.p13 chr 2NC_000002.11:g.355800T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.082C=0.918
1000GenomesAmericanSub694T=0.390C=0.610
1000GenomesEast AsianSub1008T=0.199C=0.801
1000GenomesEuropeSub1006T=0.510C=0.490
1000GenomesGlobalStudy-wide5008T=0.291C=0.709
1000GenomesSouth AsianSub978T=0.370C=0.630
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.477C=0.523
The Genome Aggregation DatabaseAfricanSub8702T=0.138C=0.862
The Genome Aggregation DatabaseAmericanSub832T=0.390C=0.610
The Genome Aggregation DatabaseEast AsianSub1622T=0.138C=0.862
The Genome Aggregation DatabaseEuropeSub18414T=0.525C=0.474
The Genome Aggregation DatabaseGlobalStudy-wide29870T=0.386C=0.613
The Genome Aggregation DatabaseOtherSub300T=0.410C=0.590
Trans-Omics for Precision MedicineGlobalStudy-wide29116T=0.314C=0.685
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.487C=0.513
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs67402494.37E-05alcohol dependence21314694

eQTL of rs6740249 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6740249 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2375068375148E06719268
chr2375714375781E06719914
chr2375798375890E06719998
chr2373724373924E06817924
chr2375068375148E06819268
chr2375421375471E06819621
chr2375714375781E06819914
chr2375798375890E06819998
chr2382866382916E06827066
chr2383307383448E06827507
chr2375068375148E06919268
chr2375421375471E06919621
chr2375714375781E06919914
chr2375798375890E06919998
chr2383307383448E06927507
chr2384034384123E06928234
chr2393769394777E07037969
chr2375068375148E07119268
chr2382591382674E07126791
chr2382866382916E07127066
chr2375068375148E07219268
chr2375421375471E07219621
chr2375714375781E07219914
chr2375798375890E07219998
chr2395880395950E07240080
chr2382591382674E07326791
chr2382866382916E07327066
chr2383307383448E07327507
chr2375068375148E07419268
chr2375421375471E07419621
chr2375714375781E07419914
chr2375798375890E07419998
chr2382591382674E07426791
chr2382866382916E07427066
chr2383307383448E07427507
chr2313241313345E081-42455
chr2313378313491E081-42309
chr2318099318380E081-37420
chr2318846318911E081-36889
chr2380093380163E08124293
chr2380180380603E08124380
chr2381199381263E08125399
chr2381298381373E08125498
chr2381416381508E08125616
chr2382071382121E08126271
chr2382183382335E08126383
chr2393769394777E08137969