rs6755400

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0263 (7876/29926,GnomAD)
G=0305 (8884/29116,TOPMED)
G=0287 (1435/5008,1000G)
G=0278 (1072/3854,ALSPAC)
G=0263 (974/3708,TWINSUK)
chr2:48073712 (GRCh38.p7) (2p16.3)
ND
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.48073712A>G
GRCh37.p13 chr 2NC_000002.11:g.48300851A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.674G=0.326
1000GenomesAmericanSub694A=0.750G=0.250
1000GenomesEast AsianSub1008A=0.906G=0.094
1000GenomesEuropeSub1006A=0.719G=0.281
1000GenomesGlobalStudy-wide5008A=0.713G=0.287
1000GenomesSouth AsianSub978A=0.540G=0.460
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.722G=0.278
The Genome Aggregation DatabaseAfricanSub8700A=0.683G=0.317
The Genome Aggregation DatabaseAmericanSub838A=0.770G=0.230
The Genome Aggregation DatabaseEast AsianSub1622A=0.917G=0.083
The Genome Aggregation DatabaseEuropeSub18464A=0.746G=0.253
The Genome Aggregation DatabaseGlobalStudy-wide29926A=0.736G=0.263
The Genome Aggregation DatabaseOtherSub302A=0.650G=0.350
Trans-Omics for Precision MedicineGlobalStudy-wide29116A=0.694G=0.305
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.737G=0.263
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs67554000.000451nicotine dependence17158188

eQTL of rs6755400 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6755400 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr24829768648297834E067-3017
chr24833302048333070E06732169
chr24833314148335114E06732290
chr24834028548340812E06739434
chr24834092348341025E06740072
chr24829768648297834E068-3017
chr24833775248337936E06836901
chr24834028548340812E06839434
chr24834092348341025E06840072
chr24829768648297834E069-3017
chr24834013048340242E06939279
chr24834028548340812E06939434
chr24833314148335114E07032290
chr24829768648297834E071-3017
chr24833302048333070E07132169
chr24833314148335114E07132290
chr24834013048340242E07139279
chr24834028548340812E07139434
chr24834092348341025E07140072
chr24829768648297834E072-3017
chr24833302048333070E07232169
chr24833302048333070E07332169
chr24833302048333070E07432169
chr24833775248337936E07436901
chr24834028548340812E07439434
chr24833314148335114E08132290









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr24833817148339582E06737320
chr24833817148339582E06837320
chr24833817148339582E06937320
chr24833817148339582E07037320
chr24833817148339582E07137320
chr24833817148339582E07237320
chr24833817148339582E07337320
chr24833817148339582E07437320
chr24833817148339582E08137320
chr24833817148339582E08237320