rs6765661

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0270 (8091/29908,GnomAD)
G=0250 (7293/29118,TOPMED)
G=0205 (1025/5008,1000G)
G=0358 (1381/3854,ALSPAC)
G=0333 (1235/3708,TWINSUK)
chr3:103929476 (GRCh38.p7) (3q13.11)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.103929476A>G
GRCh37.p13 chr 3NC_000003.11:g.103648320A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.936G=0.064
1000GenomesAmericanSub694A=0.690G=0.310
1000GenomesEast AsianSub1008A=0.838G=0.162
1000GenomesEuropeSub1006A=0.610G=0.390
1000GenomesGlobalStudy-wide5008A=0.795G=0.205
1000GenomesSouth AsianSub978A=0.830G=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.642G=0.358
The Genome Aggregation DatabaseAfricanSub8714A=0.884G=0.116
The Genome Aggregation DatabaseAmericanSub838A=0.670G=0.330
The Genome Aggregation DatabaseEast AsianSub1604A=0.829G=0.171
The Genome Aggregation DatabaseEuropeSub18450A=0.652G=0.347
The Genome Aggregation DatabaseGlobalStudy-wide29908A=0.729G=0.270
The Genome Aggregation DatabaseOtherSub302A=0.600G=0.400
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.749G=0.250
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.667G=0.333
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs67656610.000514alcohol dependence24277619

eQTL of rs6765661 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6765661 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.