SNP Detail Info-rs6765661

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0270 (8091/29908,GnomAD)
G=0250 (7293/29118,TOPMED)
G=0205 (1025/5008,1000G)
G=0358 (1381/3854,ALSPAC)
G=0333 (1235/3708,TWINSUK)

Position: chr3:103929476 (GRCh38.p7) (3q13.11)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.103929476A>G
GRCh37.p13 chr 3	NC_000003.11:g.103648320A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.936	G=0.064
1000Genomes	American	Sub	694	A=0.690	G=0.310
1000Genomes	East Asian	Sub	1008	A=0.838	G=0.162
1000Genomes	Europe	Sub	1006	A=0.610	G=0.390
1000Genomes	Global	Study-wide	5008	A=0.795	G=0.205
1000Genomes	South Asian	Sub	978	A=0.830	G=0.170
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.642	G=0.358
The Genome Aggregation Database	African	Sub	8714	A=0.884	G=0.116
The Genome Aggregation Database	American	Sub	838	A=0.670	G=0.330
The Genome Aggregation Database	East Asian	Sub	1604	A=0.829	G=0.171
The Genome Aggregation Database	Europe	Sub	18450	A=0.652	G=0.347
The Genome Aggregation Database	Global	Study-wide	29908	A=0.729	G=0.270
The Genome Aggregation Database	Other	Sub	302	A=0.600	G=0.400
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.749	G=0.250
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.667	G=0.333

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs6765661	0.000514	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs6765661