rs6767209

Homo sapiens
G>A
KCNAB1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A=0021 (651/29982,GnomAD)
A=0033 (966/29118,TOPMED)
A=0028 (139/5008,1000G)
A=0000 (1/3854,ALSPAC)
A=0000 (1/3708,TWINSUK)
chr3:156290184 (GRCh38.p7) (3q25.31)
AD
GWASdb2
1   publication(s)
See rs on genome

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.156290184G>A
GRCh37.p13 chr 3NC_000003.11:g.156007973G>A
KCNAB1 RefSeqGeneNG_042292.1:g.174637G>A

Gene: KCNAB1, potassium voltage-gated channel subfamily A member regulatory beta subunit 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KCNAB1 transcript variant 4NM_001308217.1:c.N/AIntron Variant
KCNAB1 transcript variant 2NM_003471.3:c.N/AIntron Variant
KCNAB1 transcript variant 1NM_172160.2:c.N/AIntron Variant
KCNAB1 transcript variant 5NM_001308222.1:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant 3NM_172159.3:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant X1XM_017007171.1:c.N/AIntron Variant
KCNAB1 transcript variant X7XM_017007174.1:c.N/AIntron Variant
KCNAB1 transcript variant X2XM_011513115.2:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant X3XM_011513116.2:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant X6XM_011513117.2:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant X4XM_017007172.1:c.N/AGenic Upstream Transcript Variant
KCNAB1 transcript variant X5XM_017007173.1:c.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.895A=0.105
1000GenomesAmericanSub694G=1.000A=0.000
1000GenomesEast AsianSub1008G=1.000A=0.000
1000GenomesEuropeSub1006G=1.000A=0.000
1000GenomesGlobalStudy-wide5008G=0.972A=0.028
1000GenomesSouth AsianSub978G=1.000A=0.000
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=1.000A=0.000
The Genome Aggregation DatabaseAfricanSub8712G=0.926A=0.074
The Genome Aggregation DatabaseAmericanSub838G=1.000A=0.000
The Genome Aggregation DatabaseEast AsianSub1620G=1.000A=0.000
The Genome Aggregation DatabaseEuropeSub18510G=0.999A=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29982G=0.978A=0.021
The Genome Aggregation DatabaseOtherSub302G=1.000A=0.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.966A=0.033
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=1.000A=0.000
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs67672090.000955alcohol dependence20201924

eQTL of rs6767209 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6767209 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3155964768155965042E067-42931
chr3155990970155991336E067-16637
chr3156017012156017359E0679039
chr3156017389156017704E0679416
chr3156018325156018426E06710352
chr3156021273156021344E06713300
chr3156021451156021584E06713478
chr3156038567156038760E06730594
chr3156038982156039250E06731009
chr3156039747156039833E06731774
chr3156039887156039965E06731914
chr3155990970155991336E068-16637
chr3156006967156007019E068-954
chr3156016857156016996E0688884
chr3156017012156017359E0689039
chr3156017389156017704E0689416
chr3156018325156018426E06810352
chr3156021273156021344E06813300
chr3156021451156021584E06813478
chr3156021978156022045E06814005
chr3156022166156022546E06814193
chr3156037543156037604E06829570
chr3156038039156038296E06830066
chr3156038567156038760E06830594
chr3156038982156039250E06831009
chr3156039747156039833E06831774
chr3156039887156039965E06831914
chr3155964768155965042E069-42931
chr3155975904155976059E069-31914
chr3156016857156016996E0698884
chr3156017012156017359E0699039
chr3156017389156017704E0699416
chr3156020922156020972E06912949
chr3156021273156021344E06913300
chr3156021451156021584E06913478
chr3156037543156037604E06929570
chr3156038039156038296E06930066
chr3156038567156038760E06930594
chr3156038982156039250E06931009
chr3156039747156039833E06931774
chr3156039887156039965E06931914
chr3155964768155965042E071-42931
chr3155965264155965388E071-42585
chr3155967465155967623E071-40350
chr3155990229155990308E071-17665
chr3155990970155991336E071-16637
chr3156016857156016996E0718884
chr3156017012156017359E0719039
chr3156017389156017704E0719416
chr3156018325156018426E07110352
chr3156020922156020972E07112949
chr3156021273156021344E07113300
chr3156021451156021584E07113478
chr3156037543156037604E07129570
chr3156038039156038296E07130066
chr3156038567156038760E07130594
chr3156039747156039833E07131774
chr3156039887156039965E07131914
chr3155972336155972604E072-35369
chr3156021451156021584E07213478
chr3156038039156038296E07230066
chr3156038567156038760E07230594
chr3156038982156039250E07231009
chr3156039747156039833E07231774
chr3156039887156039965E07231914
chr3155990970155991336E073-16637
chr3156016857156016996E0738884
chr3156017012156017359E0739039
chr3156017389156017704E0739416
chr3156018325156018426E07310352
chr3156021451156021584E07313478
chr3156038039156038296E07330066
chr3156038567156038760E07330594
chr3155964768155965042E074-42931
chr3155990970155991336E074-16637
chr3156020922156020972E07412949
chr3156021273156021344E07413300
chr3156021451156021584E07413478
chr3156037543156037604E07429570
chr3156038039156038296E07430066
chr3156038567156038760E07430594
chr3156038982156039250E07431009
chr3156039747156039833E07431774
chr3156039887156039965E07431914
chr3155964768155965042E081-42931
chr3156015532156015627E0817559
chr3156015940156016001E0817967
chr3156016857156016996E0818884
chr3156017012156017359E0819039
chr3156017389156017704E0819416
chr3156018325156018426E08110352
chr3156016857156016996E0828884
chr3156018325156018426E08210352









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr3156008680156009914E067707
chr3156011461156011516E0673488
chr3156008680156009914E068707
chr3156011461156011516E0683488
chr3156008680156009914E069707
chr3156011461156011516E0693488
chr3156008680156009914E070707
chr3156008680156009914E071707
chr3156011461156011516E0713488
chr3156008680156009914E072707
chr3156011461156011516E0723488
chr3156008680156009914E073707
chr3156011461156011516E0733488
chr3156008680156009914E074707
chr3156008680156009914E081707
chr3156008680156009914E082707