rs6778263

Homo sapiens
C>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0456 (13661/29912,GnomAD)
A=0456 (13285/29118,TOPMED)
A=0395 (1978/5008,1000G)
A=0463 (1783/3854,ALSPAC)
A=0493 (1828/3708,TWINSUK)
chr3:190920044 (GRCh38.p7) (3q28)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.190920044C>A
GRCh37.p13 chr 3NC_000003.11:g.190637833C>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.551A=0.449
1000GenomesAmericanSub694C=0.650A=0.350
1000GenomesEast AsianSub1008C=0.642A=0.358
1000GenomesEuropeSub1006C=0.512A=0.488
1000GenomesGlobalStudy-wide5008C=0.605A=0.395
1000GenomesSouth AsianSub978C=0.700A=0.300
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.537A=0.463
The Genome Aggregation DatabaseAfricanSub8702C=0.540A=0.460
The Genome Aggregation DatabaseAmericanSub836C=0.690A=0.310
The Genome Aggregation DatabaseEast AsianSub1604C=0.641A=0.359
The Genome Aggregation DatabaseEuropeSub18468C=0.528A=0.471
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.543A=0.456
The Genome Aggregation DatabaseOtherSub302C=0.620A=0.380
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.543A=0.456
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.507A=0.493
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs67782630.000252alcohol dependence24277619

eQTL of rs6778263 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6778263 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.