SNP Detail Info-rs680686

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0025 (751/30000,GnomAD)
A==0038 (1122/29118,TOPMED)
A==0026 (130/5008,1000G)
A==0000 (1/3854,ALSPAC)
A==0000 (0/3708,TWINSUK)

Position: chr9:15351452 (GRCh38.p7) (9p22.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 15 Enhancers around

Promoter: 10 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.15351452A>G
GRCh37.p13 chr 9	NC_000009.11:g.15351450A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.093	G=0.907
1000Genomes	American	Sub	694	A=0.010	G=0.990
1000Genomes	East Asian	Sub	1008	A=0.000	G=1.000
1000Genomes	Europe	Sub	1006	A=0.000	G=1.000
1000Genomes	Global	Study-wide	5008	A=0.026	G=0.974
1000Genomes	South Asian	Sub	978	A=0.000	G=1.000
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.000	G=1.000
The Genome Aggregation Database	African	Sub	8732	A=0.085	G=0.915
The Genome Aggregation Database	American	Sub	838	A=0.000	G=1.000
The Genome Aggregation Database	East Asian	Sub	1622	A=0.000	G=1.000
The Genome Aggregation Database	Europe	Sub	18506	A=0.000	G=0.999
The Genome Aggregation Database	Global	Study-wide	30000	A=0.025	G=0.975
The Genome Aggregation Database	Other	Sub	302	A=0.000	G=1.000
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.038	G=0.961
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.000	G=1.000

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs680686	0.000297	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr9	15351090	15351434	E069	-16
chr9	15351444	15351554	E069	0
chr9	15351090	15351434	E071	-16
chr9	15351444	15351554	E071	0
chr9	15351090	15351434	E072	-16
chr9	15370867	15371337	E072	19417
chr9	15351090	15351434	E073	-16
chr9	15351444	15351554	E073	0
chr9	15370604	15370697	E081	19154
chr9	15370707	15370851	E081	19257
chr9	15370867	15371337	E081	19417
chr9	15369274	15369476	E082	17824
chr9	15370604	15370697	E082	19154
chr9	15370707	15370851	E082	19257
chr9	15370867	15371337	E082	19417

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr9	15305588	15308020	E067	-43430
chr9	15305588	15308020	E068	-43430
chr9	15305588	15308020	E069	-43430
chr9	15305588	15308020	E070	-43430
chr9	15305588	15308020	E071	-43430
chr9	15305588	15308020	E072	-43430
chr9	15305588	15308020	E073	-43430
chr9	15305588	15308020	E074	-43430
chr9	15305588	15308020	E081	-43430
chr9	15305588	15308020	E082	-43430

rs680686