rs6810498

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0391 (11730/29934,GnomAD)
A==0376 (10967/29118,TOPMED)
A==0471 (2359/5008,1000G)
A==0411 (1585/3854,ALSPAC)
A==0423 (1568/3708,TWINSUK)
chr4:26064749 (GRCh38.p7) (4p15.2)
AD
GWASCatalog
1   publication(s)
See rs on genome
39 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.26064749A>G
GRCh37.p13 chr 4NC_000004.11:g.26066371A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.241G=0.759
1000GenomesAmericanSub694A=0.530G=0.470
1000GenomesEast AsianSub1008A=0.670G=0.330
1000GenomesEuropeSub1006A=0.429G=0.571
1000GenomesGlobalStudy-wide5008A=0.471G=0.529
1000GenomesSouth AsianSub978A=0.580G=0.420
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.411G=0.589
The Genome Aggregation DatabaseAfricanSub8708A=0.263G=0.737
The Genome Aggregation DatabaseAmericanSub838A=0.540G=0.460
The Genome Aggregation DatabaseEast AsianSub1616A=0.679G=0.321
The Genome Aggregation DatabaseEuropeSub18470A=0.420G=0.579
The Genome Aggregation DatabaseGlobalStudy-wide29934A=0.391G=0.608
The Genome Aggregation DatabaseOtherSub302A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.376G=0.623
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.423G=0.577
PMID Title Author Journal
24166409Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs68104982E-06alcohol dependence24166409

eQTL of rs6810498 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6810498 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr42602340126025133E068-41238
chr42602513426025273E068-41098
chr42602536326025430E068-40941
chr42602340126025133E069-41238
chr42606021626060566E069-5805
chr42604108226041318E070-25053
chr42604133526041524E070-24847
chr42604160826041927E070-24444
chr42605189726051959E070-14412
chr42605198626052097E070-14274
chr42605214626052247E070-14124
chr42605763326057730E070-8641
chr42606021626060566E070-5805
chr42606874026068967E0702369
chr42607610726077061E0709736
chr42601669826017601E071-48770
chr42602340126025133E071-41238
chr42606021626060566E071-5805
chr42608336426083446E07116993
chr42608347926083570E07117108
chr42608358426083940E07117213
chr42602340126025133E072-41238
chr42602340126025133E074-41238
chr42603327326033323E081-33048
chr42603340526033609E081-32762
chr42603362526034986E081-31385
chr42604981126051210E081-15161
chr42606021626060566E081-5805
chr42606086826060959E081-5412
chr42606106526061185E081-5186
chr42607610726077061E0819736
chr42610697626107271E08140605
chr42610734826107883E08140977
chr42610797526108061E08141604
chr42610811026108272E08141739
chr42610832726108658E08141956
chr42606021626060566E082-5805
chr42606086826060959E082-5412
chr42606106526061185E082-5186