SNP Detail Info-rs6811343

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

STK32B : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0156 (4671/29902,GnomAD)
A=0189 (5505/29118,TOPMED)
A=0195 (975/5008,1000G)
A=0104 (401/3854,ALSPAC)
A=0097 (359/3708,TWINSUK)

Position: chr4:5080268 (GRCh38.p7) (4p16.2)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 34 Enhancers around

Promoter: 9 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.5080268G>A
GRCh37.p13 chr 4	NC_000004.11:g.5081995G>A

Molecule type	Change	Amino acid[Codon]	SO Term
STK32B transcript variant 2	NM_001306082.1:c.	N/A	Intron Variant
STK32B transcript variant 1	NM_018401.2:c.	N/A	Intron Variant
STK32B transcript variant X1	XM_011513497.1:c.	N/A	Intron Variant
STK32B transcript variant X6	XM_005247982.3:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X8	XM_005247983.4:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X5	XM_011513501.2:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X9	XM_011513504.1:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X1	XM_017008374.1:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X2	XM_017008375.1:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X3	XM_017008376.1:c.	N/A	Genic Upstream Transcript Variant
STK32B transcript variant X5	XM_017008377.1:c.	N/A	Genic Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.679	A=0.321
1000Genomes	American	Sub	694	G=0.800	A=0.200
1000Genomes	East Asian	Sub	1008	G=0.844	A=0.156
1000Genomes	Europe	Sub	1006	G=0.897	A=0.103
1000Genomes	Global	Study-wide	5008	G=0.805	A=0.195
1000Genomes	South Asian	Sub	978	G=0.850	A=0.150
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.896	A=0.104
The Genome Aggregation Database	African	Sub	8708	G=0.718	A=0.282
The Genome Aggregation Database	American	Sub	838	G=0.820	A=0.180
The Genome Aggregation Database	East Asian	Sub	1592	G=0.820	A=0.180
The Genome Aggregation Database	Europe	Sub	18462	G=0.905	A=0.094
The Genome Aggregation Database	Global	Study-wide	29902	G=0.843	A=0.156
The Genome Aggregation Database	Other	Sub	302	G=0.910	A=0.090
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.810	A=0.189
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.903	A=0.097

PMID	Title	Author	Journal
20158304	A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.	Lind PA	Twin Res Hum Genet

SNP ID	p-value	Traits	Study
rs6811343	3.43E-05	alcohol and nictotine co-dependence	20158304

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	5034910	5035462	E068	-46533
chr4	5035478	5035643	E068	-46352
chr4	5130226	5130302	E069	48231
chr4	5130520	5130634	E069	48525
chr4	5034910	5035462	E070	-46533
chr4	5035478	5035643	E070	-46352
chr4	5035854	5036188	E070	-45807
chr4	5036232	5036346	E070	-45649
chr4	5036359	5036471	E070	-45524
chr4	5036638	5036760	E070	-45235
chr4	5036916	5036979	E070	-45016
chr4	5035478	5035643	E071	-46352
chr4	5036232	5036346	E071	-45649
chr4	5130226	5130302	E072	48231
chr4	5130520	5130634	E072	48525
chr4	5130520	5130634	E073	48525
chr4	5130226	5130302	E074	48231
chr4	5130520	5130634	E074	48525
chr4	5034910	5035462	E081	-46533
chr4	5035478	5035643	E081	-46352
chr4	5042662	5042799	E081	-39196
chr4	5042845	5044031	E081	-37964
chr4	5102842	5102975	E081	20847
chr4	5103353	5103632	E081	21358
chr4	5116264	5116360	E081	34269
chr4	5116704	5117269	E081	34709
chr4	5117307	5117357	E081	35312
chr4	5119915	5120127	E081	37920
chr4	5120173	5120398	E081	38178
chr4	5120907	5121549	E081	38912
chr4	5102842	5102975	E082	20847
chr4	5103353	5103632	E082	21358
chr4	5120907	5121549	E082	38912
chr4	5127245	5127320	E082	45250

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	5052169	5054275	E067	-27720
chr4	5052169	5054275	E068	-27720
chr4	5052169	5054275	E069	-27720
chr4	5052169	5054275	E070	-27720
chr4	5052169	5054275	E071	-27720
chr4	5052169	5054275	E072	-27720
chr4	5052169	5054275	E073	-27720
chr4	5052169	5054275	E074	-27720
chr4	5052169	5054275	E082	-27720

rs6811343