rs6814075

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0457 (13644/29842,GnomAD)
C=0460 (13414/29118,TOPMED)
C=0450 (2254/5008,1000G)
C=0490 (1890/3854,ALSPAC)
T==0499 (1851/3708,TWINSUK)
chr4:35516255 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35516255T>C
GRCh37.p13 chr 4NC_000004.11:g.35517877T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.598C=0.402
1000GenomesAmericanSub694T=0.470C=0.530
1000GenomesEast AsianSub1008T=0.700C=0.300
1000GenomesEuropeSub1006T=0.535C=0.465
1000GenomesGlobalStudy-wide5008T=0.550C=0.450
1000GenomesSouth AsianSub978T=0.400C=0.600
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.510C=0.490
The Genome Aggregation DatabaseAfricanSub8694T=0.588C=0.412
The Genome Aggregation DatabaseAmericanSub836T=0.430C=0.570
The Genome Aggregation DatabaseEast AsianSub1606T=0.738C=0.262
The Genome Aggregation DatabaseEuropeSub18404T=0.508C=0.491
The Genome Aggregation DatabaseGlobalStudy-wide29842T=0.542C=0.457
The Genome Aggregation DatabaseOtherSub302T=0.580C=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.539C=0.460
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.499C=0.501
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs68140750.000126nicotine dependence17158188

eQTL of rs6814075 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6814075 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E0748860
chr43553670135536912E08218824
chr43553699835537160E08219121


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E0688995
chr43552703435527236E0689157
chr43552753335527608E0689656
chr43552687235526986E0698995
chr43552703435527236E0699157
chr43552687235526986E0718995
chr43552703435527236E0719157
chr43552753335527608E0719656
chr43552687235526986E0728995
chr43552703435527236E0729157
chr43552687235526986E0738995
chr43552703435527236E0739157
chr43552687235526986E0748995
chr43552703435527236E0749157