rs6824735

Homo sapiens
T>C
GLRA3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
T==0358 (10699/29876,GnomAD)
T==0395 (11528/29118,TOPMED)
T==0441 (2211/5008,1000G)
T==0278 (1073/3854,ALSPAC)
T==0288 (1067/3708,TWINSUK)
chr4:174819418 (GRCh38.p7) (4q34.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.174819418T>C
GRCh37.p13 chr 4NC_000004.11:g.175740569T>C

Gene: GLRA3, glycine receptor alpha 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
GLRA3 transcript variant 2NM_001042543.2:c.N/AIntron Variant
GLRA3 transcript variant 1NM_006529.3:c.N/AIntron Variant
GLRA3 transcript variant X4XM_011532267.2:c.N/AIntron Variant
GLRA3 transcript variant X1XM_017008630.1:c.N/AIntron Variant
GLRA3 transcript variant X5XM_011532268.2:c.N/AGenic Upstream Transcript Variant
GLRA3 transcript variant X2XR_001741328.1:n.N/AIntron Variant
GLRA3 transcript variant X3XR_001741329.1:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.551C=0.449
1000GenomesAmericanSub694T=0.460C=0.540
1000GenomesEast AsianSub1008T=0.544C=0.456
1000GenomesEuropeSub1006T=0.312C=0.688
1000GenomesGlobalStudy-wide5008T=0.441C=0.559
1000GenomesSouth AsianSub978T=0.310C=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.278C=0.722
The Genome Aggregation DatabaseAfricanSub8678T=0.495C=0.505
The Genome Aggregation DatabaseAmericanSub836T=0.470C=0.530
The Genome Aggregation DatabaseEast AsianSub1608T=0.532C=0.468
The Genome Aggregation DatabaseEuropeSub18452T=0.273C=0.726
The Genome Aggregation DatabaseGlobalStudy-wide29876T=0.358C=0.641
The Genome Aggregation DatabaseOtherSub302T=0.350C=0.650
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.395C=0.604
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.288C=0.712
PMID Title Author Journal

P-Value

SNP ID p-value Traits Study
rs68247353.9E-05alcoholismpha002893

eQTL of rs6824735 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6824735 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr4175749808175751102E0679239
chr4175749808175751102E0689239
chr4175749808175751102E0699239
chr4175749808175751102E0709239
chr4175749808175751102E0719239
chr4175749808175751102E0729239
chr4175749808175751102E0739239
chr4175749808175751102E0749239
chr4175749808175751102E0819239
chr4175749808175751102E0829239