SNP Detail Info-rs6833974

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC729307 : Non Coding Transcript Variant
LOC105377441 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0184 (5529/29918,GnomAD)
A==0153 (4465/29118,TOPMED)
A==0152 (762/5008,1000G)
A==0228 (878/3854,ALSPAC)
A==0234 (866/3708,TWINSUK)

Position: chr4:137197929 (GRCh38.p7) (4q28.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 6 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.137197929A>G
GRCh37.p13 chr 4	NC_000004.11:g.138119083A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LINC02510 transcript	NR_134640.1:n.113...NR_134640.1:n.1138A>G	A>G	Non Coding Transcript Variant

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105377441 transcript variant X1	XR_001741835.1:n.	N/A	Intron Variant
LOC105377441 transcript variant X2	XR_001741836.1:n.	N/A	Genic Upstream Transcript Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.019	G=0.981
1000Genomes	American	Sub	694	A=0.340	G=0.660
1000Genomes	East Asian	Sub	1008	A=0.089	G=0.911
1000Genomes	Europe	Sub	1006	A=0.250	G=0.750
1000Genomes	Global	Study-wide	5008	A=0.152	G=0.848
1000Genomes	South Asian	Sub	978	A=0.160	G=0.840
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.228	G=0.772
The Genome Aggregation Database	African	Sub	8708	A=0.052	G=0.948
The Genome Aggregation Database	American	Sub	834	A=0.320	G=0.680
The Genome Aggregation Database	East Asian	Sub	1608	A=0.095	G=0.905
The Genome Aggregation Database	Europe	Sub	18466	A=0.249	G=0.750
The Genome Aggregation Database	Global	Study-wide	29918	A=0.184	G=0.815
The Genome Aggregation Database	Other	Sub	302	A=0.150	G=0.850
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.153	G=0.846
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.234	G=0.766

PMID	Title	Author	Journal
23743675	A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.	Kapoor M	Hum Genet

SNP ID	p-value	Traits	Study
rs6833974	1.48E-05	alcohol consumption	23743675

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	138127852	138128346	E070	8769
chr4	138127852	138128346	E074	8769
chr4	138134603	138134662	E074	15520
chr4	138134825	138135023	E074	15742
chr4	138127852	138128346	E081	8769
chr4	138127852	138128346	E082	8769

rs6833974