rs6834581

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0337 (10087/29932,GnomAD)
C=0424 (12360/29118,TOPMED)
C=0444 (2223/5008,1000G)
C=0245 (944/3854,ALSPAC)
C=0225 (833/3708,TWINSUK)
chr4:38786613 (GRCh38.p7) (4p14)
AD
GWASdb2
1   publication(s)
See rs on genome
40 Enhancers around
26 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.38786613T>C
GRCh37.p13 chr 4NC_000004.11:g.38788234T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.337C=0.663
1000GenomesAmericanSub694T=0.750C=0.250
1000GenomesEast AsianSub1008T=0.519C=0.481
1000GenomesEuropeSub1006T=0.722C=0.278
1000GenomesGlobalStudy-wide5008T=0.556C=0.444
1000GenomesSouth AsianSub978T=0.590C=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.755C=0.245
The Genome Aggregation DatabaseAfricanSub8698T=0.392C=0.608
The Genome Aggregation DatabaseAmericanSub838T=0.780C=0.220
The Genome Aggregation DatabaseEast AsianSub1616T=0.538C=0.462
The Genome Aggregation DatabaseEuropeSub18478T=0.798C=0.202
The Genome Aggregation DatabaseGlobalStudy-wide29932T=0.663C=0.337
The Genome Aggregation DatabaseOtherSub302T=0.550C=0.450
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.575C=0.424
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.775C=0.225
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs68345818.18E-06alcohol consumption23743675

eQTL of rs6834581 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6834581 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43876089838761605E067-26629
chr43875394338755431E068-32803
chr43876089838761605E069-26629
chr43874051238740745E071-47489
chr43874081238740864E071-47370
chr43875307438753285E071-34949
chr43875333838753545E071-34689
chr43875356438753626E071-34608
chr43875394338755431E071-32803
chr43875968438759867E071-28367
chr43876089838761605E071-26629
chr43876222738762320E071-25914
chr43876407238764727E071-23507
chr43880262538802717E07114391
chr43880272438802921E07114490
chr43880308438803124E07114850
chr43881807538818437E07129841
chr43881856438818649E07130330
chr43876089838761605E072-26629
chr43876172238761850E072-26384
chr43876190738761976E072-26258
chr43876222738762320E072-25914
chr43881807538818437E07229841
chr43875333838753545E074-34689
chr43875356438753626E074-34608
chr43875957638759666E074-28568
chr43875968438759867E074-28367
chr43876089838761605E074-26629
chr43876172238761850E074-26384
chr43876190738761976E074-26258
chr43876222738762320E074-25914
chr43877100638771202E074-17032
chr43874503938745146E081-43088
chr43875105738751361E081-36873
chr43875158138751637E081-36597
chr43875163938751719E081-36515
chr43875394338755431E081-32803
chr43875105738751361E082-36873
chr43875158138751637E082-36597
chr43875163938751719E082-36515








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43880566838807737E06717434
chr43880436838804525E06816134
chr43880467738804759E06816443
chr43880523438805284E06817000
chr43880566838807737E06817434
chr43880523438805284E06917000
chr43880566838807737E06917434
chr43880403138804077E07115797
chr43880417738804308E07115943
chr43880436838804525E07116134
chr43880467738804759E07116443
chr43880523438805284E07117000
chr43880566838807737E07117434
chr43880436838804525E07216134
chr43880467738804759E07216443
chr43880523438805284E07217000
chr43880566838807737E07217434
chr43880467738804759E07316443
chr43880523438805284E07317000
chr43880566838807737E07317434
chr43880403138804077E07415797
chr43880417738804308E07415943
chr43880436838804525E07416134
chr43880467738804759E07416443
chr43880523438805284E07417000
chr43880566838807737E07417434