SNP Detail Info-rs6836406

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

LOC105377564 : Intron Variant

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0393 (11751/29888,GnomAD)
G=0316 (9226/29118,TOPMED)
G=0307 (1539/5008,1000G)
G=0482 (1858/3854,ALSPAC)
G=0496 (1841/3708,TWINSUK)

Position: chr4:179981761 (GRCh38.p7) (4q34.3)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.179981761A>G
GRCh37.p13 chr 4	NC_000004.11:g.180902914A>G

Molecule type	Change	Amino acid[Codon]	SO Term
LOC105377564 transcript variant X2	XR_001741480.1:n.	N/A	Intron Variant
LOC105377564 transcript variant X1	XR_939516.2:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.862	G=0.138
1000Genomes	American	Sub	694	A=0.670	G=0.330
1000Genomes	East Asian	Sub	1008	A=0.671	G=0.329
1000Genomes	Europe	Sub	1006	A=0.550	G=0.450
1000Genomes	Global	Study-wide	5008	A=0.693	G=0.307
1000Genomes	South Asian	Sub	978	A=0.650	G=0.350
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.518	G=0.482
The Genome Aggregation Database	African	Sub	8704	A=0.814	G=0.186
The Genome Aggregation Database	American	Sub	836	A=0.620	G=0.380
The Genome Aggregation Database	East Asian	Sub	1608	A=0.659	G=0.341
The Genome Aggregation Database	Europe	Sub	18438	A=0.503	G=0.496
The Genome Aggregation Database	Global	Study-wide	29888	A=0.606	G=0.393
The Genome Aggregation Database	Other	Sub	302	A=0.660	G=0.340
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.683	G=0.316
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.504	G=0.496

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs6836406	0.00072	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs6836406