SNP Detail Info-rs6836440

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.99127355G>A
GRCh37.p13 chr 4	NC_000004.11:g.100048506G>A

Molecule type	Change	Amino acid[Codon]	SO Term
ADH4 transcript variant 3	NM_000670.4:c.	N/A	Intron Variant
ADH4 transcript variant 1	NM_001306171.1:c.	N/A	Intron Variant
ADH4 transcript variant 2	NM_001306172.1:c.	N/A	Intron Variant
ADH4 transcript variant X1	XM_017007713.1:c.	N/A	Intron Variant
ADH4 transcript variant X2	XM_017007714.1:c.	N/A	Intron Variant
ADH4 transcript variant X3	XM_017007715.1:c.	N/A	Intron Variant

Molecule type	Change	Amino acid[Codon]	SO Term
LOC100507053 transcript	NR_037884.1:n.	N/A	Intron Variant

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.070	A=0.930
1000Genomes	American	Sub	694	G=0.060	A=0.940
1000Genomes	East Asian	Sub	1008	G=0.001	A=0.999
1000Genomes	Europe	Sub	1006	G=0.026	A=0.974
1000Genomes	Global	Study-wide	5008	G=0.036	A=0.964
1000Genomes	South Asian	Sub	978	G=0.020	A=0.980
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.026	A=0.974
The Exome Aggregation Consortium	American	Sub	21954	G=0.068	A=0.931
The Exome Aggregation Consortium	Asian	Sub	25160	G=0.012	A=0.987
The Exome Aggregation Consortium	Europe	Sub	73284	G=0.031	A=0.968
The Exome Aggregation Consortium	Global	Study-wide	121304	G=0.034	A=0.965
The Exome Aggregation Consortium	Other	Sub	906	G=0.030	A=0.970
The Genome Aggregation Database	African	Sub	8722	G=0.062	A=0.938
The Genome Aggregation Database	American	Sub	838	G=0.060	A=0.940
The Genome Aggregation Database	East Asian	Sub	1622	G=0.001	A=0.999
The Genome Aggregation Database	Europe	Sub	18494	G=0.035	A=0.964
The Genome Aggregation Database	Global	Study-wide	29978	G=0.042	A=0.957
The Genome Aggregation Database	Other	Sub	302	G=0.020	A=0.980
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.044	A=0.956
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.030	A=0.970

PMID	Title	Author	Journal
24166409	Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci.	Gelernter J	Mol Psychiatry
21083667	Haplotype-based study of the association of alcohol-metabolizing genes with alcohol dependence in four independent populations.	Liu J	Alcohol Clin Exp Res
18331377	Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.	Kuo PH	Alcohol Clin Exp Res
21244703	Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data.	Wang JH	Genome Med

SNP ID	p-value	Traits	Study
rs6836440	2E-06	alcohol dependence	24166409

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr4	100006643	100006704	E070	-41802
chr4	100006873	100006947	E070	-41559
chr4	100012091	100012363	E071	-36143
chr4	100006873	100006947	E081	-41559
chr4	100007948	100008019	E081	-40487
chr4	100006643	100006704	E082	-41802
chr4	100006873	100006947	E082	-41559

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr4	100008829	100008950	E067	-39556
chr4	100009042	100010625	E067	-37881
chr4	100010636	100011572	E067	-36934
chr4	100008829	100008950	E068	-39556
chr4	100009042	100010625	E068	-37881
chr4	100010636	100011572	E068	-36934
chr4	100008645	100008721	E069	-39785
chr4	100008829	100008950	E069	-39556
chr4	100009042	100010625	E069	-37881
chr4	100010636	100011572	E069	-36934
chr4	100008158	100008256	E070	-40250
chr4	100008370	100008613	E070	-39893
chr4	100008645	100008721	E070	-39785
chr4	100008829	100008950	E070	-39556
chr4	100009042	100010625	E070	-37881
chr4	100010636	100011572	E070	-36934
chr4	100009042	100010625	E071	-37881
chr4	100010636	100011572	E071	-36934
chr4	100008829	100008950	E072	-39556
chr4	100009042	100010625	E072	-37881
chr4	100010636	100011572	E072	-36934
chr4	100008829	100008950	E073	-39556
chr4	100009042	100010625	E073	-37881
chr4	100010636	100011572	E073	-36934
chr4	100009042	100010625	E074	-37881
chr4	100010636	100011572	E074	-36934
chr4	100008645	100008721	E081	-39785
chr4	100008829	100008950	E081	-39556
chr4	100009042	100010625	E081	-37881
chr4	100010636	100011572	E081	-36934
chr4	100007472	100007769	E082	-40737
chr4	100008158	100008256	E082	-40250
chr4	100008370	100008613	E082	-39893
chr4	100008645	100008721	E082	-39785
chr4	100008829	100008950	E082	-39556
chr4	100009042	100010625	E082	-37881
chr4	100010636	100011572	E082	-36934

rs6836440