rs6836555

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0486 (14503/29836,GnomAD)
C==0456 (13294/29116,TOPMED)
C==0489 (2451/5008,1000G)
T=0497 (1915/3854,ALSPAC)
C==0493 (1829/3708,TWINSUK)
chr4:35556858 (GRCh38.p7) (4p15.1)
ND
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.35556858C>T
GRCh37.p13 chr 4NC_000004.11:g.35558480C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.394T=0.606
1000GenomesAmericanSub694C=0.460T=0.540
1000GenomesEast AsianSub1008C=0.704T=0.296
1000GenomesEuropeSub1006C=0.526T=0.474
1000GenomesGlobalStudy-wide5008C=0.489T=0.511
1000GenomesSouth AsianSub978C=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.503T=0.497
The Genome Aggregation DatabaseAfricanSub8688C=0.408T=0.592
The Genome Aggregation DatabaseAmericanSub834C=0.420T=0.580
The Genome Aggregation DatabaseEast AsianSub1610C=0.742T=0.258
The Genome Aggregation DatabaseEuropeSub18402C=0.502T=0.497
The Genome Aggregation DatabaseGlobalStudy-wide29836C=0.486T=0.513
The Genome Aggregation DatabaseOtherSub302C=0.570T=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.456T=0.543
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.493T=0.507
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs68365550.000149nicotine dependence17158188

eQTL of rs6836555 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6836555 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr43552673735526787E074-31693
chr43553670135536912E082-21568
chr43553699835537160E082-21320


Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr43552687235526986E068-31494
chr43552703435527236E068-31244
chr43552753335527608E068-30872
chr43552687235526986E069-31494
chr43552703435527236E069-31244
chr43552687235526986E071-31494
chr43552703435527236E071-31244
chr43552753335527608E071-30872
chr43552687235526986E072-31494
chr43552703435527236E072-31244
chr43552687235526986E073-31494
chr43552703435527236E073-31244
chr43552687235526986E074-31494
chr43552703435527236E074-31244