rs683979

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0433 (12945/29852,GnomAD)
T=0483 (2419/5008,1000G)
T=0358 (1379/3854,ALSPAC)
T=0363 (1345/3708,TWINSUK)
chr18:68186551 (GRCh38.p7) (18q22.1)
ND
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.68186551C>T
GRCh37.p13 chr 18NC_000018.9:g.65853788C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.452T=0.548
1000GenomesAmericanSub694C=0.590T=0.410
1000GenomesEast AsianSub1008C=0.507T=0.493
1000GenomesEuropeSub1006C=0.652T=0.348
1000GenomesGlobalStudy-wide5008C=0.517T=0.483
1000GenomesSouth AsianSub978C=0.430T=0.570
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.642T=0.358
The Genome Aggregation DatabaseAfricanSub8710C=0.456T=0.544
The Genome Aggregation DatabaseAmericanSub828C=0.540T=0.460
The Genome Aggregation DatabaseEast AsianSub1610C=0.507T=0.493
The Genome Aggregation DatabaseEuropeSub18404C=0.622T=0.377
The Genome Aggregation DatabaseGlobalStudy-wide29852C=0.566T=0.433
The Genome Aggregation DatabaseOtherSub300C=0.700T=0.300
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.637T=0.363
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs6839790.000938nicotine dependence17158188

eQTL of rs683979 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs683979 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr186588828365888988E07034495
chr186588828365888988E08234495