rs6869903

Homo sapiens
T>C
CTNND2 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0303 (9062/29842,GnomAD)
C=0319 (9311/29118,TOPMED)
C=0267 (1337/5008,1000G)
C=0290 (1117/3854,ALSPAC)
C=0271 (1005/3708,TWINSUK)
chr5:11300742 (GRCh38.p7) (5p15.2)
AD
GWASdb2
1   publication(s)
See rs on genome
243 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.11300742T>C
GRCh37.p13 chr 5NC_000005.9:g.11300854T>C
CTNND2 RefSeqGeneNG_023544.1:g.608257A>G

Gene: CTNND2, catenin delta 2(minus strand)

Molecule type Change Amino acid[Codon] SO Term
CTNND2 transcript variant 2NM_001288715.1:c.N/AIntron Variant
CTNND2 transcript variant 3NM_001288716.1:c.N/AIntron Variant
CTNND2 transcript variant 4NM_001288717.1:c.N/AIntron Variant
CTNND2 transcript variant 1NM_001332.3:c.N/AIntron Variant
CTNND2 transcript variant 5NR_109988.1:n.N/AIntron Variant
CTNND2 transcript variant X1XM_005248251.3:c.N/AIntron Variant
CTNND2 transcript variant X2XM_005248252.2:c.N/AIntron Variant
CTNND2 transcript variant X3XM_005248253.1:c.N/AIntron Variant
CTNND2 transcript variant X4XM_011513967.2:c.N/AIntron Variant
CTNND2 transcript variant X5XM_017009072.1:c.N/AIntron Variant
CTNND2 transcript variant X6XM_017009073.1:c.N/AIntron Variant
CTNND2 transcript variant X7XM_017009074.1:c.N/AIntron Variant
CTNND2 transcript variant X8XM_017009075.1:c.N/AIntron Variant
CTNND2 transcript variant X9XM_017009076.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.635C=0.365
1000GenomesAmericanSub694T=0.640C=0.360
1000GenomesEast AsianSub1008T=0.811C=0.189
1000GenomesEuropeSub1006T=0.743C=0.257
1000GenomesGlobalStudy-wide5008T=0.733C=0.267
1000GenomesSouth AsianSub978T=0.840C=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.710C=0.290
The Genome Aggregation DatabaseAfricanSub8666T=0.635C=0.365
The Genome Aggregation DatabaseAmericanSub834T=0.640C=0.360
The Genome Aggregation DatabaseEast AsianSub1612T=0.841C=0.159
The Genome Aggregation DatabaseEuropeSub18428T=0.714C=0.285
The Genome Aggregation DatabaseGlobalStudy-wide29842T=0.696C=0.303
The Genome Aggregation DatabaseOtherSub302T=0.750C=0.250
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.680C=0.319
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.729C=0.271
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs68699030.000347alcohol dependence20201924

eQTL of rs6869903 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6869903 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr51125226611252352E067-48502
chr51125540511255568E067-45286
chr51125567911255733E067-45121
chr51126139611261686E067-39168
chr51126734511267452E067-33402
chr51126748211267657E067-33197
chr51126769011267779E067-33075
chr51126896811269018E067-31836
chr51126916311269231E067-31623
chr51127372111273862E067-26992
chr51128928711289426E067-11428
chr51128953411289682E067-11172
chr51128973411289784E067-11070
chr51129001411290104E067-10750
chr51129315711293386E067-7468
chr51129374811294050E067-6804
chr51129437011294706E067-6148
chr51130666211306827E0675808
chr51132383011323892E06722976
chr51132397511324205E06723121
chr51132423411324278E06723380
chr51132476711324867E06723913
chr51132497111325313E06724117
chr51132605611326112E06725202
chr51132992611330160E06729072
chr51125128211251429E068-49425
chr51125145311251647E068-49207
chr51125226611252352E068-48502
chr51125737511257531E068-43323
chr51125758811257674E068-43180
chr51126139611261686E068-39168
chr51126405011264100E068-36754
chr51126683011267009E068-33845
chr51126734511267452E068-33402
chr51126748211267657E068-33197
chr51126769011267779E068-33075
chr51126896811269018E068-31836
chr51126916311269231E068-31623
chr51128928711289426E068-11428
chr51128953411289682E068-11172
chr51128973411289784E068-11070
chr51129001411290104E068-10750
chr51129437011294706E068-6148
chr51130666211306827E0685808
chr51131352111313571E06812667
chr51131364911313699E06812795
chr51131937011319410E06818516
chr51131941411319468E06818560
chr51132004711320589E06819193
chr51132205311322113E06821199
chr51132229411322371E06821440
chr51132238711322584E06821533
chr51132306611323213E06822212
chr51132348911323587E06822635
chr51132383011323892E06822976
chr51132397511324205E06823121
chr51132476711324867E06823913
chr51132497111325313E06824117
chr51132605611326112E06825202
chr51132992611330160E06829072
chr51133061711330779E06829763
chr51134647611346679E06845622
chr51134723311347589E06846379
chr51134865011348732E06847796
chr51134910311349178E06848249
chr51125128211251429E069-49425
chr51125145311251647E069-49207
chr51125226611252352E069-48502
chr51125275511252890E069-47964
chr51125294711253023E069-47831
chr51125540511255568E069-45286
chr51125567911255733E069-45121
chr51125737511257531E069-43323
chr51125758811257674E069-43180
chr51126139611261686E069-39168
chr51126649811266677E069-34177
chr51126683011267009E069-33845
chr51126734511267452E069-33402
chr51126748211267657E069-33197
chr51126769011267779E069-33075
chr51126896811269018E069-31836
chr51126916311269231E069-31623
chr51127372111273862E069-26992
chr51128845011288601E069-12253
chr51128928711289426E069-11428
chr51128953411289682E069-11172
chr51128973411289784E069-11070
chr51129001411290104E069-10750
chr51132205311322113E06921199
chr51132229411322371E06921440
chr51132238711322584E06921533
chr51132306611323213E06922212
chr51132348911323587E06922635
chr51132383011323892E06922976
chr51132397511324205E06923121
chr51132423411324278E06923380
chr51132476711324867E06923913
chr51132497111325313E06924117
chr51132605611326112E06925202
chr51132992611330160E06929072
chr51126139611261686E070-39168
chr51126649811266677E070-34177
chr51126683011267009E070-33845
chr51126734511267452E070-33402
chr51128845011288601E070-12253
chr51128928711289426E070-11428
chr51128953411289682E070-11172
chr51128973411289784E070-11070
chr51125128211251429E071-49425
chr51125145311251647E071-49207
chr51125226611252352E071-48502
chr51125275511252890E071-47964
chr51125294711253023E071-47831
chr51125308911253169E071-47685
chr51125540511255568E071-45286
chr51125567911255733E071-45121
chr51125737511257531E071-43323
chr51125758811257674E071-43180
chr51126683011267009E071-33845
chr51126734511267452E071-33402
chr51126748211267657E071-33197
chr51126769011267779E071-33075
chr51126896811269018E071-31836
chr51126916311269231E071-31623
chr51128845011288601E071-12253
chr51128928711289426E071-11428
chr51128953411289682E071-11172
chr51128973411289784E071-11070
chr51129315711293386E071-7468
chr51129374811294050E071-6804
chr51130666211306827E0715808
chr51132205311322113E07121199
chr51132229411322371E07121440
chr51132238711322584E07121533
chr51132383011323892E07122976
chr51132397511324205E07123121
chr51132423411324278E07123380
chr51132497111325313E07124117
chr51132605611326112E07125202
chr51132992611330160E07129072
chr51134723311347589E07146379
chr51125128211251429E072-49425
chr51125145311251647E072-49207
chr51125226611252352E072-48502
chr51125275511252890E072-47964
chr51126139611261686E072-39168
chr51126405011264100E072-36754
chr51126734511267452E072-33402
chr51126748211267657E072-33197
chr51126769011267779E072-33075
chr51126896811269018E072-31836
chr51126916311269231E072-31623
chr51128845011288601E072-12253
chr51128928711289426E072-11428
chr51128953411289682E072-11172
chr51128973411289784E072-11070
chr51129315711293386E072-7468
chr51129374811294050E072-6804
chr51129437011294706E072-6148
chr51131352111313571E07212667
chr51131364911313699E07212795
chr51131937011319410E07218516
chr51131941411319468E07218560
chr51132004711320589E07219193
chr51132229411322371E07221440
chr51132238711322584E07221533
chr51132397511324205E07223121
chr51132423411324278E07223380
chr51132476711324867E07223913
chr51132497111325313E07224117
chr51132605611326112E07225202
chr51133061711330779E07229763
chr51125128211251429E073-49425
chr51125145311251647E073-49207
chr51126139611261686E073-39168
chr51126896811269018E073-31836
chr51126916311269231E073-31623
chr51128928711289426E073-11428
chr51128953411289682E073-11172
chr51128973411289784E073-11070
chr51129001411290104E073-10750
chr51129315711293386E073-7468
chr51132306611323213E07322212
chr51132348911323587E07322635
chr51132383011323892E07322976
chr51132397511324205E07323121
chr51132423411324278E07323380
chr51132476711324867E07323913
chr51132497111325313E07324117
chr51134723311347589E07346379
chr51125128211251429E074-49425
chr51125145311251647E074-49207
chr51125540511255568E074-45286
chr51125567911255733E074-45121
chr51125737511257531E074-43323
chr51125758811257674E074-43180
chr51126139611261686E074-39168
chr51126405011264100E074-36754
chr51126734511267452E074-33402
chr51126748211267657E074-33197
chr51126769011267779E074-33075
chr51126896811269018E074-31836
chr51126916311269231E074-31623
chr51127372111273862E074-26992
chr51128845011288601E074-12253
chr51128928711289426E074-11428
chr51128953411289682E074-11172
chr51128973411289784E074-11070
chr51129001411290104E074-10750
chr51129315711293386E074-7468
chr51129374811294050E074-6804
chr51129437011294706E074-6148
chr51130666211306827E0745808
chr51131352111313571E07412667
chr51131364911313699E07412795
chr51131391511314134E07413061
chr51132229411322371E07421440
chr51132238711322584E07421533
chr51132306611323213E07422212
chr51132348911323587E07422635
chr51132383011323892E07422976
chr51132397511324205E07423121
chr51132423411324278E07423380
chr51132476711324867E07423913
chr51132497111325313E07424117
chr51132605611326112E07425202
chr51126649811266677E081-34177
chr51126683011267009E081-33845
chr51126734511267452E081-33402
chr51126748211267657E081-33197
chr51126769011267779E081-33075
chr51128845011288601E081-12253
chr51128928711289426E081-11428
chr51128953411289682E081-11172
chr51128973411289784E081-11070
chr51129001411290104E081-10750
chr51134647611346679E08145622
chr51134723311347589E08146379
chr51126649811266677E082-34177
chr51128845011288601E082-12253
chr51128928711289426E082-11428
chr51128953411289682E082-11172
chr51128973411289784E082-11070