rs6870730

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0435 (13024/29914,GnomAD)
G==0491 (14304/29118,TOPMED)
A=0399 (1996/5008,1000G)
A=0366 (1412/3854,ALSPAC)
A=0351 (1302/3708,TWINSUK)
chr5:116825255 (GRCh38.p7) (5q23.1)
AD
GWASdb2
1   publication(s)
See rs on genome
20 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.116825255G>A
GRCh37.p13 chr 5NC_000005.9:g.116160951G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.273A=0.727
1000GenomesAmericanSub694G=0.620A=0.380
1000GenomesEast AsianSub1008G=0.840A=0.160
1000GenomesEuropeSub1006G=0.639A=0.361
1000GenomesGlobalStudy-wide5008G=0.601A=0.399
1000GenomesSouth AsianSub978G=0.750A=0.250
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.634A=0.366
The Genome Aggregation DatabaseAfricanSub8700G=0.296A=0.704
The Genome Aggregation DatabaseAmericanSub838G=0.670A=0.330
The Genome Aggregation DatabaseEast AsianSub1610G=0.817A=0.183
The Genome Aggregation DatabaseEuropeSub18464G=0.663A=0.336
The Genome Aggregation DatabaseGlobalStudy-wide29914G=0.564A=0.435
The Genome Aggregation DatabaseOtherSub302G=0.630A=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.491A=0.508
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.649A=0.351
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs68707300.00093alcohol dependence20201924

eQTL of rs6870730 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6870730 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr5116114530116114646E067-46305
chr5116114530116114646E068-46305
chr5116114657116115007E068-45944
chr5116114530116114646E070-46305
chr5116114657116115007E070-45944
chr5116150796116151001E070-9950
chr5116151927116152348E070-8603
chr5116113696116114479E071-46472
chr5116114530116114646E071-46305
chr5116114657116115007E071-45944
chr5116113696116114479E081-46472
chr5116150796116151001E081-9950
chr5116201448116201683E08140497
chr5116201749116201865E08140798
chr5116201979116202029E08141028
chr5116114530116114646E082-46305
chr5116114657116115007E082-45944
chr5116149859116149909E082-11042
chr5116150513116150754E082-10197
chr5116150796116151001E082-9950