rs687415

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0123 (3693/29902,GnomAD)
C==0153 (4470/29118,TOPMED)
C==0126 (633/5008,1000G)
C==0089 (343/3854,ALSPAC)
C==0092 (340/3708,TWINSUK)
chr2:165447088 (GRCh38.p7) (2q24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
34 Enhancers around
81 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.165447088C>T
GRCh37.p13 chr 2NC_000002.11:g.166303598C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.275T=0.725
1000GenomesAmericanSub694C=0.110T=0.890
1000GenomesEast AsianSub1008C=0.061T=0.939
1000GenomesEuropeSub1006C=0.084T=0.916
1000GenomesGlobalStudy-wide5008C=0.126T=0.874
1000GenomesSouth AsianSub978C=0.050T=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.089T=0.911
The Genome Aggregation DatabaseAfricanSub8710C=0.233T=0.767
The Genome Aggregation DatabaseAmericanSub838C=0.070T=0.930
The Genome Aggregation DatabaseEast AsianSub1584C=0.041T=0.959
The Genome Aggregation DatabaseEuropeSub18468C=0.081T=0.918
The Genome Aggregation DatabaseGlobalStudy-wide29902C=0.123T=0.876
The Genome Aggregation DatabaseOtherSub302C=0.130T=0.870
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.153T=0.846
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.092T=0.908
PMID Title Author Journal
22481050Genetic influences on craving for alcohol.Agrawal AAddict Behav

P-Value

SNP ID p-value Traits Study
rs6874153.15E-05alcohol craving with or without dependence22481050

eQTL of rs687415 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs687415 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2166296819166297243E068-6355
chr2166336457166336568E06832859
chr2166336604166336666E06833006
chr2166336690166336743E06833092
chr2166336457166336568E06932859
chr2166262690166263265E070-40333
chr2166281323166281406E070-22192
chr2166296819166297243E070-6355
chr2166297383166297557E070-6041
chr2166330772166330831E07027174
chr2166331326166331435E07027728
chr2166262690166263265E071-40333
chr2166330459166330509E07126861
chr2166330772166330831E07127174
chr2166330459166330509E07226861
chr2166330772166330831E07227174
chr2166296658166296712E073-6886
chr2166296819166297243E073-6355
chr2166330772166330831E07327174
chr2166331326166331435E07327728
chr2166262690166263265E074-40333
chr2166330459166330509E07426861
chr2166330772166330831E07427174
chr2166331326166331435E07427728
chr2166262690166263265E081-40333
chr2166309099166309190E0815501
chr2166309571166309698E0815973
chr2166309983166310777E0816385
chr2166310865166310915E0817267
chr2166330772166330831E08127174
chr2166331326166331435E08127728
chr2166262690166263265E082-40333
chr2166296658166296712E082-6886
chr2166308329166308481E0824731









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr2166325756166326678E06722158
chr2166326686166327003E06723088
chr2166327033166327136E06723435
chr2166327209166327289E06723611
chr2166327708166327802E06724110
chr2166327990166328500E06724392
chr2166329432166329786E06725834
chr2166325420166325661E06821822
chr2166325756166326678E06822158
chr2166326686166327003E06823088
chr2166327033166327136E06823435
chr2166327209166327289E06823611
chr2166327708166327802E06824110
chr2166327990166328500E06824392
chr2166329432166329786E06825834
chr2166329837166329914E06826239
chr2166332271166332320E06828673
chr2166325756166326678E06922158
chr2166326686166327003E06923088
chr2166327033166327136E06923435
chr2166327209166327289E06923611
chr2166327708166327802E06924110
chr2166327990166328500E06924392
chr2166329432166329786E06925834
chr2166329837166329914E06926239
chr2166332271166332320E06928673
chr2166325420166325661E07021822
chr2166325756166326678E07022158
chr2166326686166327003E07023088
chr2166327033166327136E07023435
chr2166327209166327289E07023611
chr2166327708166327802E07024110
chr2166327990166328500E07024392
chr2166329432166329786E07025834
chr2166329837166329914E07026239
chr2166325420166325661E07121822
chr2166325756166326678E07122158
chr2166326686166327003E07123088
chr2166327033166327136E07123435
chr2166327990166328500E07124392
chr2166329432166329786E07125834
chr2166329837166329914E07126239
chr2166332271166332320E07128673
chr2166325756166326678E07222158
chr2166326686166327003E07223088
chr2166327033166327136E07223435
chr2166327209166327289E07223611
chr2166327708166327802E07224110
chr2166327990166328500E07224392
chr2166329432166329786E07225834
chr2166329837166329914E07226239
chr2166332271166332320E07228673
chr2166325756166326678E07322158
chr2166326686166327003E07323088
chr2166327033166327136E07323435
chr2166327209166327289E07323611
chr2166327708166327802E07324110
chr2166327990166328500E07324392
chr2166325420166325661E07421822
chr2166325756166326678E07422158
chr2166326686166327003E07423088
chr2166329432166329786E07425834
chr2166332271166332320E07428673
chr2166325420166325661E08121822
chr2166325756166326678E08122158
chr2166326686166327003E08123088
chr2166327033166327136E08123435
chr2166327209166327289E08123611
chr2166327708166327802E08124110
chr2166327990166328500E08124392
chr2166329432166329786E08125834
chr2166325420166325661E08221822
chr2166325756166326678E08222158
chr2166326686166327003E08223088
chr2166327033166327136E08223435
chr2166327209166327289E08223611
chr2166327708166327802E08224110
chr2166327990166328500E08224392
chr2166329432166329786E08225834
chr2166329837166329914E08226239
chr2166332271166332320E08228673