rs6877560

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0168 (5051/29946,GnomAD)
A==0149 (4360/29118,TOPMED)
A==0175 (878/5008,1000G)
A==0212 (818/3854,ALSPAC)
A==0218 (807/3708,TWINSUK)
chr5:82619482 (GRCh38.p7) (5q14.2)
OD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.82619482A>G
GRCh37.p13 chr 5NC_000005.9:g.81915301A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.042G=0.958
1000GenomesAmericanSub694A=0.160G=0.840
1000GenomesEast AsianSub1008A=0.220G=0.780
1000GenomesEuropeSub1006A=0.189G=0.811
1000GenomesGlobalStudy-wide5008A=0.175G=0.825
1000GenomesSouth AsianSub978A=0.310G=0.690
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.212G=0.788
The Genome Aggregation DatabaseAfricanSub8724A=0.068G=0.932
The Genome Aggregation DatabaseAmericanSub836A=0.170G=0.830
The Genome Aggregation DatabaseEast AsianSub1616A=0.224G=0.776
The Genome Aggregation DatabaseEuropeSub18468A=0.211G=0.788
The Genome Aggregation DatabaseGlobalStudy-wide29946A=0.168G=0.831
The Genome Aggregation DatabaseOtherSub302A=0.150G=0.850
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.149G=0.850
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.218G=0.782
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs68775600.000118Opioid sensitivity23183491

eQTL of rs6877560 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6877560 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr58193673081937701E06721429
chr58193781781937948E06722516
chr58193796281938087E06722661
chr58193586481935996E06820563
chr58193673081937701E06821429
chr58193483081934899E06919529
chr58193495381935025E06919652
chr58193507081935242E06919769
chr58193527981935510E06919978
chr58193554781935845E06920246
chr58193586481935996E06920563
chr58193600081936067E06920699
chr58193673081937701E06921429
chr58193459881934770E07019297
chr58193483081934899E07019529
chr58193495381935025E07019652
chr58193507081935242E07019769
chr58193527981935510E07019978
chr58193554781935845E07020246
chr58193586481935996E07020563
chr58193600081936067E07020699
chr58193673081937701E07021429
chr58194057181940773E07025270
chr58193495381935025E07119652
chr58193507081935242E07119769
chr58193527981935510E07119978
chr58193673081937701E07121429
chr58193673081937701E07221429
chr58193459881934770E07319297
chr58193483081934899E07319529
chr58193495381935025E07319652
chr58193507081935242E07319769
chr58193527981935510E07319978
chr58193554781935845E07320246
chr58188156581881649E081-33652
chr58188168881881751E081-33550
chr58189189581891945E081-23356
chr58189231481892954E081-22347
chr58189334281893547E081-21754
chr58193459881934770E08119297
chr58193483081934899E08119529
chr58193495381935025E08119652
chr58193507081935242E08119769
chr58193527981935510E08119978
chr58193554781935845E08120246
chr58193586481935996E08120563
chr58193600081936067E08120699
chr58193673081937701E08121429
chr58193781781937948E08122516
chr58193796281938087E08122661
chr58193828281938427E08122981
chr58195207181952851E08136770
chr58195291981952997E08137618
chr58195300281953080E08137701
chr58195324281953351E08137941
chr58188201581883089E082-32212
chr58193483081934899E08219529
chr58193495381935025E08219652
chr58193507081935242E08219769
chr58193527981935510E08219978
chr58193554781935845E08220246
chr58193586481935996E08220563
chr58193600081936067E08220699
chr58194057181940773E08225270