rs6877560

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A==0168 (5051/29946,GnomAD)
A==0149 (4360/29118,TOPMED)
A==0175 (878/5008,1000G)
A==0212 (818/3854,ALSPAC)
A==0218 (807/3708,TWINSUK)

Position: chr5:82619482 (GRCh38.p7) (5q14.2)

Phenotype: OD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 64 Enhancers around

Promoter: 0 Promoter around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.82619482A>G
GRCh37.p13 chr 5	NC_000005.9:g.81915301A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.042	G=0.958
1000Genomes	American	Sub	694	A=0.160	G=0.840
1000Genomes	East Asian	Sub	1008	A=0.220	G=0.780
1000Genomes	Europe	Sub	1006	A=0.189	G=0.811
1000Genomes	Global	Study-wide	5008	A=0.175	G=0.825
1000Genomes	South Asian	Sub	978	A=0.310	G=0.690
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.212	G=0.788
The Genome Aggregation Database	African	Sub	8724	A=0.068	G=0.932
The Genome Aggregation Database	American	Sub	836	A=0.170	G=0.830
The Genome Aggregation Database	East Asian	Sub	1616	A=0.224	G=0.776
The Genome Aggregation Database	Europe	Sub	18468	A=0.211	G=0.788
The Genome Aggregation Database	Global	Study-wide	29946	A=0.168	G=0.831
The Genome Aggregation Database	Other	Sub	302	A=0.150	G=0.850
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.149	G=0.850
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.218	G=0.782

PMID	Title	Author	Journal
23183491	Genome-wide association study identifies a potent locus associated with human opioid sensitivity.	Nishizawa D	Mol Psychiatry

SNP ID	p-value	Traits	Study
rs6877560	0.000118	Opioid sensitivity	23183491

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	81936730	81937701	E067	21429
chr5	81937817	81937948	E067	22516
chr5	81937962	81938087	E067	22661
chr5	81935864	81935996	E068	20563
chr5	81936730	81937701	E068	21429
chr5	81934830	81934899	E069	19529
chr5	81934953	81935025	E069	19652
chr5	81935070	81935242	E069	19769
chr5	81935279	81935510	E069	19978
chr5	81935547	81935845	E069	20246
chr5	81935864	81935996	E069	20563
chr5	81936000	81936067	E069	20699
chr5	81936730	81937701	E069	21429
chr5	81934598	81934770	E070	19297
chr5	81934830	81934899	E070	19529
chr5	81934953	81935025	E070	19652
chr5	81935070	81935242	E070	19769
chr5	81935279	81935510	E070	19978
chr5	81935547	81935845	E070	20246
chr5	81935864	81935996	E070	20563
chr5	81936000	81936067	E070	20699
chr5	81936730	81937701	E070	21429
chr5	81940571	81940773	E070	25270
chr5	81934953	81935025	E071	19652
chr5	81935070	81935242	E071	19769
chr5	81935279	81935510	E071	19978
chr5	81936730	81937701	E071	21429
chr5	81936730	81937701	E072	21429
chr5	81934598	81934770	E073	19297
chr5	81934830	81934899	E073	19529
chr5	81934953	81935025	E073	19652
chr5	81935070	81935242	E073	19769
chr5	81935279	81935510	E073	19978
chr5	81935547	81935845	E073	20246
chr5	81881565	81881649	E081	-33652
chr5	81881688	81881751	E081	-33550
chr5	81891895	81891945	E081	-23356
chr5	81892314	81892954	E081	-22347
chr5	81893342	81893547	E081	-21754
chr5	81934598	81934770	E081	19297
chr5	81934830	81934899	E081	19529
chr5	81934953	81935025	E081	19652
chr5	81935070	81935242	E081	19769
chr5	81935279	81935510	E081	19978
chr5	81935547	81935845	E081	20246
chr5	81935864	81935996	E081	20563
chr5	81936000	81936067	E081	20699
chr5	81936730	81937701	E081	21429
chr5	81937817	81937948	E081	22516
chr5	81937962	81938087	E081	22661
chr5	81938282	81938427	E081	22981
chr5	81952071	81952851	E081	36770
chr5	81952919	81952997	E081	37618
chr5	81953002	81953080	E081	37701
chr5	81953242	81953351	E081	37941
chr5	81882015	81883089	E082	-32212
chr5	81934830	81934899	E082	19529
chr5	81934953	81935025	E082	19652
chr5	81935070	81935242	E082	19769
chr5	81935279	81935510	E082	19978
chr5	81935547	81935845	E082	20246
chr5	81935864	81935996	E082	20563
chr5	81936000	81936067	E082	20699
chr5	81940571	81940773	E082	25270

rs6877560

Genomic Coordinates

Population Frequency

P-Value

eQTL of rs6877560 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs6877560 in Fetal Brain

Genomic View

Chromatin Interaction

Enhancer Annotation (GRCh37.p13)