rs6881283

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0206 (6172/29894,GnomAD)
T=0170 (4952/29118,TOPMED)
T=0198 (992/5008,1000G)
T=0250 (963/3854,ALSPAC)
T=0243 (901/3708,TWINSUK)
chr5:91759840 (GRCh38.p7) (5q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
8 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.91759840C>T
GRCh37.p13 chr 5NC_000005.9:g.91055657C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.952T=0.048
1000GenomesAmericanSub694C=0.700T=0.300
1000GenomesEast AsianSub1008C=0.721T=0.279
1000GenomesEuropeSub1006C=0.774T=0.226
1000GenomesGlobalStudy-wide5008C=0.802T=0.198
1000GenomesSouth AsianSub978C=0.780T=0.220
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.750T=0.250
The Genome Aggregation DatabaseAfricanSub8714C=0.918T=0.082
The Genome Aggregation DatabaseAmericanSub834C=0.710T=0.290
The Genome Aggregation DatabaseEast AsianSub1612C=0.722T=0.278
The Genome Aggregation DatabaseEuropeSub18432C=0.745T=0.254
The Genome Aggregation DatabaseGlobalStudy-wide29894C=0.793T=0.206
The Genome Aggregation DatabaseOtherSub302C=0.770T=0.230
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.829T=0.170
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.757T=0.243
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs68812830.0000558alcoholismpha002892
rs68812830.000056alcohol dependence(early age of onset)20201924
rs68812830.00011alcohol dependence20201924

eQTL of rs6881283 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs6881283 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr59103800791038307E070-17350
chr59103858791038771E070-16886
chr59102566591025715E081-29942
chr59102585391026285E081-29372
chr59102639591026456E081-29201
chr59102585391026285E082-29372
chr59102639591026456E082-29201
chr59103691491037138E082-18519